Combined live attenuated viral vaccine
ATC code: J07BD52 (Measles-mumps-rubella vaccine (MMR))
Live attenuated measles (Edmonston-Zagreb or Schwarz), mumps (Jeryl Lynn), and rubella (RA 27/3) viruses. After injection, viruses briefly replicate and induce full humoral and cellular immunity comparable to natural infection. Effectiveness after 2 doses: measles 97%, mumps 88%, rubella 97%.
First line
MMR during breastfeeding. CDC ACIP 2024 and AEP CAV 2024 – compatible. Although live, vaccine viruses are not shed in milk in active form. If unvaccinated before pregnancy and rubella-susceptible – vaccinate immediately postpartum, no breastfeeding interruption.
Opens the checker prefilled with this drug. Pick the second one from your regimen.
Contraindicated in pregnancy. Contraception for 1 month after vaccination. Accidental vaccination in early pregnancy is not grounds for termination (no observed teratogenicity – monitor).
Fully compatible. Vaccine viruses are not shed in milk in active form. If rubella-susceptible – vaccinate immediately postpartum. Hale L1.
Reference information, not a clinical decision. Discuss feeding pauses or changes with your physician or an IBCLC.
MMR – measles, mumps, rubella vaccine (live) is evaluated for the following indications with varying evidence strength: Vaccination during breastfeeding (evidence tier A). See the full indication matrix with dosing and citations above on this page.
Common side effects of MMR – measles, mumps, rubella vaccine (live) (≥ 1 in 100): Injection-site pain, Fever 7-12 days post-vaccination (5-15%), Measles-like rash (5%), Arthralgia in adult women (25% from rubella component). See the Safety section for uncommon and serious reactions.
FDA category X. Contraindicated in pregnancy. Contraception for 1 month after vaccination. Accidental vaccination in early pregnancy is not grounds for termination (no observed teratogenicity – monitor).
Fully compatible. Vaccine viruses are not shed in milk in active form. If rubella-susceptible – vaccinate immediately postpartum. Hale L1.
MMR – measles, mumps, rubella vaccine (live) is contraindicated in: Pregnancy (live vaccine); Severe immunodeficiency; Anaphylaxis to previous dose or components (neomycin, gelatin); Untreated active tuberculosis. Full list in the Safety section.