Drugs
Evigrade catalog. Every drug is evaluated per drug-indication pair against international clinical guidelines
How to read tiers A–F
- AStrong evidence – first or second line in international guidelines
- BRecommended in selected cases
- CStudy data contradict each other
- DBenefit not proven, no documented harm
- FDocumented harm, or risk without benefit
Tier
Popular
No proven benefit
Best studied
Supplements and vitamins
Heart and blood vessels
Brain and mental health
Infections
Digestion and metabolism
Breathing and allergy
All drugs as a list
- 5-hydroxytryptophan (5-HTP)
- Abiraterone
- Aceclofenac
- Acetyl-L-carnitine
- Acetylcysteine
- Acetylsalicylic acid
- Aciclovir
- Aclidinium
- Adalimumab
- Ademetionine
- Aged garlic extract (AGE, Kyolic)
- Agomelatine
- Alendronic acid
- Alloferon (Allokin-alfa)
- Allopurinol
- Almagate
- Almotriptan
- Alpha-lipoic acid (thioctic acid, ALA)
- Alpha-tocopherol
- Alprazolam
- Ambroxol
- Aminodihydrophthalazinedione sodium
- Amiodarone
- Amisulpride
- Amitriptyline
- Amlodipine
- Amlodipine + Olmesartan
- Amlodipine + Olmesartan + Hydrochlorothiazide
- Amlodipine + Valsartan
- Amlodipine + Valsartan + Hydrochlorothiazide
- Amorolfine
- Amoxicillin
- Amoxicillin + Clavulanic Acid
- Amphotericin B
- Anaferon (anti-human interferon gamma antibodies in homeopathic dilutions)
- Anas Barbariae Hepatis et Cordis Extractum (homeopathic)
- Anastrozole
- Andrographis paniculata
- Antibodies to S-100 brain-specific protein (homeopathic)
- Apigenin
- Apixaban
- Aripiprazole
- Artichoke (Cynara scolymus)
- Ascorbic acid
- Ashwagandha (Withania somnifera)
- Astaxanthin
- Astragalus root (Astragalus membranaceus; Huang Qi in traditional Chinese medicine)
- Atazanavir
- Atenolol
- Atomoxetine
- Atorvastatin
- Atorvastatin + Ezetimibe
- Azathioprine
- Azilsartan medoxomil
- Azilsartan medoxomil + chlorthalidone
- Azithromycin
- Azoximer bromide
- Bacopa monnieri (brahmi)
- Bacterial lysates OM-85
- Beclomethasone dipropionate
- Beetroot juice / dietary nitrate (Beta vulgaris)
- Benzocaine
- Benzydamine
- Berberine
- Beta-1,3/1,6-D-glucan (yeast or oat)
- Beta-alanine
- Beta-carotene
- Beta-hydroxy beta-methylbutyrate (HMB)
- Betahistine
- Betaine (trimethylglycine, TMG)
- Betaine hydrochloride
- Betamethasone
- Bicalutamide
- Bifidobacterium longum
- Bilastine
- Bilberry (Vaccinium myrtillus fruit extract)
- Bimatoprost
- Biotin
- Bisacodyl
- Bisoprolol
- Black cohosh (Cimicifuga racemosa)
- Black seed (Nigella sativa)
- Boron
- Boswellia
- Brimonidine
- Brivudine
- Bromazepam
- Bromelain (pineapple enzyme)
- Bromhexine
- Bromocriptine
- Budesonide
- Budesonide/formoterol
- Buprenorphine (transdermal)
- Bupropion
- Cabergoline
- Caffeine
- Calcifediol (25-hydroxyvitamin D)
- Calcipotriol
- Calcium (oral salts: carbonate, citrate, lactate, gluconate)
- Calcium + Cholecalciferol
- Calcium carbonate
- Calcium D-glucarate
- Calcium dobesilate
- Candesartan
- Candesartan + Hydrochlorothiazide
- Capecitabine
- Capsaicin
- Captopril
- Carbamazepine
- Carbocisteine
- Carbomer
- Carvedilol
- Cat's claw
- Cefalexin
- Cefditoren pivoxil
- Ceftriaxone
- Cefuroxime axetil
- Celecoxib
- Cerebrolysin (porcine brain peptides)
- Cetirizine
- Cetylpyridinium
- Chaga (Inonotus obliquus)
- Chamomile (Matricaria chamomilla / recutita, flowers)
- Chloramphenicol
- Chlorella
- Chlorhexidine
- Chlorophyll (chlorophyllin copper-sodium complex)
- Chloropyramine
- Chlorpheniramine
- Chlorpromazine
- Chlortalidone
- Cholecalciferol
- Cholecalciferol + menaquinone-7 (D3+K2 combo)
- Choline (umbrella: bitartrate, phosphatidylcholine, lecithin)
- Choline alfoscerate
- Choline bitartrate
- Chromium picolinate
- Ciclopirox
- Ciclosporin
- Cinitapride
- Cinnarizine
- Ciprofloxacin
- Cisapride
- Citalopram
- Citicoline
- Clarithromycin
- Clindamycin
- Clobazam
- Clonidine
- Cloperastine
- Clopidogrel
- Clotrimazole
- Clozapine
- Co-trimoxazole
- Cobicistat
- Cod liver oil
- Colchicine
- Conjugated linoleic acid (CLA)
- Copper
- Copper intrauterine device
- Cordyceps (Cordyceps sinensis, Cordyceps militaris)
- Cortexin (bovine brain cortex polypeptides)
- COVID-19 vaccine, mRNA (Moderna)
- COVID-19 vaccine, mRNA (Pfizer-BioNTech)
- Cranberry (Vaccinium macrocarpon)
- Creatine monohydrate
- Curcumin (Curcuma longa extract)
- Cyanocobalamin
- Cyproterone acetate
- Cyproterone acetate + Ethinylestradiol
- Cytoflavin (succinic acid, nicotinamide, riboflavin, inosine complex)
- D-aspartic acid (DAA)
- D-chiro-inositol
- D-ribose
- Dabigatran
- Dapagliflozin
- Daptomycin
- Darunavir
- Deferasirox
- Deflazacort
- Deglycyrrhizinated licorice (DGL)
- Dehydroepiandrosterone (DHEA, prasterone)
- Denosumab
- Deproteinized hemoderivative from calf blood
- Desloratadine
- Desogestrel
- Dexamethasone
- Dexchlorpheniramine
- Dexketoprofen
- Dextromethorphan
- Diazepam
- Diclofenac
- Digoxin
- Dihydroergotamine
- Diindolylmethane (DIM)
- Diltiazem
- Dimenhydrinate
- Dimethyl Fumarate
- Dimetindene
- Diosmectite
- Diosmin/hesperidin
- Diphenhydramine
- Disopyramide
- Disulfiram
- Dofetilide
- Domperidone
- Donepezil
- Dong quai (Angelica sinensis)
- Dorzolamide
- Doxazosin
- Doxycycline
- Doxylamine
- Doxylamine/pyridoxine
- Dronedarone
- Droperidol
- Drospirenone + ethinylestradiol
- Drotaverine
- Duloxetine
- Dutasteride
- Dutasteride + Tamsulosin
- Dydrogesterone
- Ebastine
- Echinacea purpurea (juice/extract)
- Efavirenz
- Elderberry (Sambucus nigra)
- Eletriptan
- Eleutherococcus senticosus («Siberian ginseng»)
- Eltrombopag
- Empagliflozin
- Enalapril
- Enalapril + Hydrochlorothiazide
- Enoxaparin sodium
- Enoxolone
- Entecavir
- Epigallocatechin-3-gallate (EGCG, main green tea polyphenol)
- Eplerenone
- Ergoferon (antibodies to γ-interferon, CD4, and histamine in homeopathic dilutions)
- Ergotamine
- Erythromycin
- Escitalopram
- Eslicarbazepine acetate
- Esomeprazole
- Essential phospholipids
- Estradiol
- Estradiol + Nomegestrol acetate
- Estradiol valerate + Dienogest
- Ethanol
- Ethinylestradiol
- Ethinylestradiol + Desogestrel
- Ethinylestradiol + Gestodene
- Ethinylestradiol + Levonorgestrel
- Ethinylestradiol + Norgestimate
- Ethylmethylhydroxypyridine succinate
- Etonogestrel (implant)
- Etonogestrel + Ethinylestradiol (vaginal ring)
- Etoricoxib
- Everolimus
- Exemestane
- Ezetimibe
- Fabomotizole
- Famciclovir
- Famotidine
- Febuxostat
- Fentanyl
- Fesoterodine
- Fexofenadine
- Finasteride
- Fisetin (flavonol from strawberries, mangoes and onions)
- Flecainide
- Flucloxacillin
- Fluconazole
- Fludrocortisone
- Flunarizine
- Fluorouracil
- Fluoxetine
- Flurbiprofen
- Fluticasone
- Fluticasone furoate (nasal)
- Fluticasone propionate
- Fluvastatin
- Fluvoxamine
- Folic acid
- Follitropin alfa
- Formoterol
- Fosfomycin
- Frovatriptan
- Furosemide
- Gabapentin
- Galantamine
- Gamma-aminobutyric acid (GABA)
- Garcinia cambogia (hydroxycitric acid, HCA)
- Gemfibrozil
- Gentamicin
- Ginkgo biloba extract
- Glibenclamide
- Gliclazide
- Glimepiride
- Glucomannan (Amorphophallus konjac)
- Glucosamine
- Glucosamine + Chondroitin
- Glucosaminyl muramyl dipeptide
- Glutathione
- Glycerol
- Glycine (as a marketed «nootropic»)
- Glycyrrhizic acid + phospholipids
- Granisetron
- Grape seed extract (Vitis vinifera, oligomeric proanthocyanidins)
- Guaifenesin
- Haloperidol
- Hawthorn (Crataegus monogyna / laevigata)
- Hepatitis A vaccine, inactivated
- Hepatitis B vaccine, recombinant
- Hidrosmin
- Holy basil, tulsi (Ocimum sanctum, Ocimum tenuiflorum)
- Hopantenic acid (calcium hopantenate)
- Horsetail
- HPV vaccine, nonavalent
- Huperzine A (Huperzia serrata)
- Hyaluronic Acid (oral)
- Hydralazine
- Hydrochlorothiazide
- Hydrocortisone
- Hydrolysed Collagen Peptides (type I and III)
- Hydroxocobalamin
- Hydroxychloroquine
- Hydroxyzine
- Hyoscine butylbromide
- Hypericum perforatum
- Hypromellose
- Ibuprofen
- Imudon (polyvalent bacterial lysate)
- Inactivated influenza vaccine
- Indapamide
- Indole-3-carbinol (I3C)
- Inosine pranobex
- Insulin
- Insulin aspart
- Insulin degludec
- Insulin detemir
- Insulin glargine
- Insulin glulisine
- Insulin human isophane (NPH)
- Insulin lispro
- Interferon alpha-2b (nasal formulations)
- Interferon α-2b in suppositories
- Inulin (chicory/agave/Jerusalem artichoke prebiotic)
- Iodine (umbrella: potassium iodide, kelp / Fucus vesiculosus)
- Iopromide
- Ipratropium bromide
- Irbesartan
- Irbesartan + Hydrochlorothiazide
- Iron oral (salts: sulfate, bisglycinate, fumarate, gluconate, polymaltose; heme iron polypeptide, lactoferrin)
- Isavuconazole
- Isopropanol
- Isosorbide dinitrate
- Isosorbide mononitrate
- Isotretinoin
- Itraconazole
- Ivabradine
- Ivy leaf dry extract (Hedera helix)
- Kagocel
- Ketoconazole
- Ketoprofen
- Ketorolac
- Ketotifen
- Krill oil
- L-arginine
- L-citrulline (free form and L-citrulline malate for sports formulas)
- L-glutamine (free amino acid)
- L-lysine
- L-ornithine
- L-ornithine-L-aspartate (LOLA)
- L-theanine
- L-threonine + pyridoxine (Biotredin)
- L-tryptophan
- L-tyrosine
- Labetalol
- Lacosamide
- Lactobacillus rhamnosus GG (LGG)
- Lactoferrin
- Lamotrigine
- Lansoprazole
- Latanoprost
- Lecithin (soy or sunflower phosphatidylcholine)
- Leflunomide
- Lenalidomide
- Lercanidipine
- Letrozole
- Levetiracetam
- Levocarnitine (L-carnitine)
- Levocetirizine
- Levodopa + Carbidopa + Entacapone
- Levofloxacin
- Levomefolate (L-methylfolate, 5-MTHF)
- Levonorgestrel
- Levonorgestrel (intrauterine system)
- Levothyroxine sodium
- Licorice root (Glycyrrhiza glabra, root and rhizome; including deglycyrrhizinated DGL)
- Lidocaine
- Linagliptin
- Linezolid
- Lion's mane (Hericium erinaceus)
- Lion's Mane Mushroom (Hericium erinaceus)
- Liraglutide
- Lisinopril
- Lithium
- Loperamide
- Loratadine
- Lorazepam
- Lormetazepam
- Lornoxicam
- Losartan
- Losartan + Hydrochlorothiazide
- Lovastatin
- Lutein
- Lutein + zeaxanthin
- Lycopene
- Maca
- Magnesium (oral salts: citrate, glycinate, oxide, sulfate)
- Magnesium hydroxide
- Magnesium L-threonate (Magtein)
- Magnesium sulfate
- Manganese
- Manidipine
- Mastic gum
- Mebeverine
- Medium-chain triglycerides (MCT, coconut oil C8–C10)
- Medroxyprogesterone acetate depot
- Meglumine acridone acetate
- Melatonin
- Meldonium
- Melissa officinalis (leaf extract)
- Meloxicam
- Memantine
- Menaquinone (vitamin K2)
- Menaquinone-7
- Meperidine
- Meropenem
- Mesalazine
- Metamizole sodium
- Metformin
- Methadone
- Methotrexate
- Methylcobalamin
- Methyldopa
- Methylphenidate
- Methylprednisolone
- Methylsulfonylmethane (MSM)
- Methylthioninium chloride (methylene blue)
- Metoclopramide
- Metoprolol
- Metronidazole
- Miconazole
- Mifepristone
- Minoxidil
- Mirabegron
- Mirtazapine
- Mixed tocopherols
- MMR – measles, mumps, rubella vaccine (live)
- Moclobemide
- Molybdenum
- Mometasone
- Mometasone furoate (nasal)
- Monolaurin (glycerol monolaurate)
- Montelukast
- Morphine
- Moxifloxacin
- Moxonidine
- Mucuna pruriens (velvet bean)
- Mupirocin
- Mycophenolate mofetil
- Myo-inositol
- N-acetyl-L-tyrosine
- Naloxone
- Naproxen
- Naratriptan
- Nattokinase (serine protease from fermented soybean natto, Bacillus subtilis var. natto)
- Nebivolol
- Nicotinamide
- Nicotinamide mononucleotide (NMN)
- Nicotinamide riboside (NR)
- Nicotine
- Nicotinic acid (niacin)
- Nifedipine
- Nifuroxazide
- Nimesulide
- Nintedanib
- Nitroglycerin
- Noopept (N-phenylacetyl-L-prolylglycine ethyl ester)
- Norelgestromin + Ethinylestradiol (transdermal patch)
- Norethisterone
- Norfloxacin
- Nystatin
- Olanzapine
- Olive leaf extract (Olea europaea, oleuropein)
- Olmesartan + Hydrochlorothiazide
- Olmesartan medoxomil
- Omega-3 triglycerides (EPA and DHA)
- Omega-6 polyunsaturated fatty acids (linoleic acid and GLA)
- Omega-9 monounsaturated fatty acid (oleic acid)
- Omeprazole
- Ondansetron
- Orlistat
- Oseltamivir
- Otilonium bromide
- Oxycodone
- Oxycodone + Naloxone
- Oxymetazoline
- Oxytocin
- Paliperidone
- Palmitoylethanolamide
- Panax ginseng (Korean/Chinese ginseng)
- Pancreatin
- Pantoprazole
- Pantothenic acid
- Paracetamol
- Paracetamol + Chlorpheniramine + Phenylephrine
- Paroxetine
- Passionflower (Passiflora incarnata, aerial parts)
- Perindopril + Indapamide
- Phenazepam
- Phenelzine
- Phenibut
- Phenobarbital
- Phenylpiracetam (fonturacetam)
- Phenytoin
- Phosphatidylserine
- Phosphorus
- Phytomenadione
- Picamilon (nicotinoyl-GABA)
- Pimavanserin
- Pimozide
- Pioglitazone
- Piracetam
- Piracetam + cinnarizine
- Pirfenidone
- Pitavastatin
- Pneumococcal conjugate vaccine PCV20
- Pomalidomide
- Posaconazole
- Potassium citrate
- Potassium iodide
- Povidone-iodine
- Pramipexole
- Pravastatin
- Prednisolone
- Prednisone
- Pregabalin
- Pregnenolone
- Probiotics (Lactobacillus spp., Bifidobacterium spp., Saccharomyces boulardii)
- Progesterone, micronized
- Promethazine
- Propafenone
- Propiverine
- Propolis (bee product)
- Propranolol
- Proteolytic enzyme complex (bromelain, papain, pancreatin, trypsin, chymotrypsin, rutoside)
- Pseudoephedrine
- Psyllium (Plantago ovata, ispaghula husk)
- Pterostilbene (dimethyl resveratrol analogue)
- Pumpkin seed extract
- Pumpkin seed oil (Cucurbita pepo, Cucurbita maxima)
- Pycnogenol (French maritime pine bark extract, Pinus pinaster)
- Pygeum africanum
- Pyridoxine (vitamin B6)
- Pyrroloquinoline quinone (PQQ)
- Quercetin
- Quetiapine
- Quinidine
- Rabeprazole
- Ramipril
- Ranolazine
- Rasagiline
- Red clover (Trifolium pratense)
- Reishi (Ganoderma lucidum, lingzhi)
- Repaglinide
- Resveratrol
- Retinol
- Rhodiola rosea (golden root)
- Riboflavin
- Rifabutin
- Rifampicin
- Riociguat
- Risedronic acid
- Risperidone
- Ritonavir
- Rivaroxaban
- Rivastigmine
- Rizatriptan
- Roflumilast
- Ropinirole
- Rosuvastatin
- Rosuvastatin + Ezetimibe
- Royal jelly
- RSV vaccine, recombinant (maternal)
- Rupatadine
- Saccharomyces boulardii CNCM I-745
- Sacubitril + Valsartan
- Saffron (Crocus sativus stigma extract)
- Salbutamol (Albuterol)
- Salmeterol
- Salmeterol + Fluticasone
- Saw palmetto (Serenoa repens)
- Schisandra chinensis (magnolia berry)
- Sea buckthorn
- Selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro)
- Selegiline
- Selenium (oral salts and chelates: selenomethionine, sodium selenite, selenium yeast)
- Semaglutide
- Semax (Met-Glu-His-Phe-Pro-Gly-Pro)
- Sertraline
- Sildenafil
- Silicon (organic silicon, silica from horsetail or bamboo)
- Silodosin
- Silymarin (Silybum marianum)
- Simeticone
- Simvastatin
- Simvastatin + Ezetimibe
- Sirolimus
- Sitagliptin
- Sitagliptin + Metformin
- Slippery elm (inner bark)
- Sodium alginate
- Sodium bicarbonate
- Sodium deoxyribonucleate (Derinat)
- Sodium lauryl sulfoacetate
- Sodium picosulfate
- Solifenacin
- Somatropin
- Sotalol
- Spermidine
- Spironolactone
- Spirulina
- Stinging nettle leaf
- Stinging nettle root (Urtica dioica, radix)
- Sulfasalazine
- Sulforaphane (isothiocyanate from broccoli sprouts)
- Sumatriptan
- Sunitinib
- Tacrolimus
- Tadalafil
- Tamoxifen
- Tamsulosin
- Tapentadol
- Taurine
- Tauroursodeoxycholic acid (TUDCA)
- Tdap – tetanus, diphtheria, acellular pertussis vaccine
- Telmisartan
- Telmisartan + Hydrochlorothiazide
- Terbinafine
- Tetryzoline
- Theophylline
- Thiamazole
- Thiamine
- Thiocolchicoside
- Tibolone
- Ticagrelor
- Tilorone
- Timolol
- Tinidazole
- Tiotropium
- Tirzepatide
- Tocotrienols
- Tolperisone
- Tolterodine
- Tongkat ali (Eurycoma longifolia)
- Topiramate
- Torasemide
- Tramadol
- Tramadol + Paracetamol
- Tranexamic acid
- Tranylcypromine
- Travoprost
- Trazodone
- Triamterene
- Tribulus terrestris (puncture vine)
- Trimebutine
- Trimethoprim
- Trospium
- Turkey tail (Trametes versicolor, Coriolus versicolor)
- Ubidecarenone (coenzyme Q10)
- Ulipristal acetate
- Umifenovir
- Urolithin A (ellagitannin metabolite, mitophagy activator)
- Ursodeoxycholic acid
- Ustekinumab
- Valacyclovir
- Valeriana officinalis (root extract)
- Valproic acid
- Valsartan
- Valsartan + Hydrochlorothiazide
- Vardenafil
- Venlafaxine
- Verapamil
- Vildagliptin
- Vildagliptin + Metformin
- Vincristine
- Vinpocetine
- Vitaglutam
- Vitamin B12 (cobalamin)
- Vitex agnus-castus (chasteberry, monk's pepper)
- Voriconazole
- Vortioxetine
- Warfarin
- Xylometazoline
- Zeaxanthin
- Zinc (oral salts: picolinate, citrate, gluconate, oxide, acetate)
- Ziprasidone
- Zolmitriptan
- Zolpidem
- Zonisamide
- α-Glutamyl-L-tryptophan