Evigrade

Sea buckthorn

Herbal preparation, sea buckthorn berries and seeds (Hippophae rhamnoides); in Russia sea buckthorn oil is a registered medicinal product for topical use

ATC code: A11JA-SEA-BUCKTHORN

Brand names – supplements: Sibu Sea Buckthorn, NOW Sea Buckthorn Oil, Genesis Today Sea Buckthorn, Weleda Sea BuckthornSupplements are not tested in clinical trials and are not registered as medications.

Updated · Methodology

Indications

C

Local burn and damaged-skin care

Adjunct

In Russia sea buckthorn oil is registered by the Ministry of Health as a medicinal product for topical use in first- and second-degree burns, radiation skin injury, trophic ulcers and pressure ulcers. The oil is applied as a thin layer to the damaged surface twice daily until epithelialisation. The evidence base is small Soviet-era clinical studies, not Western-style RCTs. The ISBI Practice Guidelines for Burn Care (Burns 2016) do not mention sea buckthorn – the international standard for superficial burn care rests on cooling, panthenol gels, silver sulfadiazine creams and non-adherent dressings. In Spain and most EU countries sea buckthorn oil is not registered as a burn medication. If a patient is in Russia and a doctor prescribed sea buckthorn oil for a superficial burn, the use follows the national pharmacopoeia. In deep burns, burns of face, hands, feet or covering more than 5% of body surface, sea buckthorn does not replace specialised burn-centre care.

ICD-10: T20-T32 · ICD-11: ND90-ND9Z

D

Hemorrhoidal disease

Adjunct

In Russia sea buckthorn rectal suppositories are registered for haemorrhoids, anal fissures and proctitis in the healing phase. Suppositories are inserted once or twice daily after defecation for 10–14 days. The evidence base consists of Soviet-era clinical studies and case series; Western-style RCTs are absent. International haemorrhoid guidelines (ASCRS 2018, ESCP 2020) do not include sea buckthorn; first-line therapy in stage 1–2 disease is bowel-habit normalisation, flavonoids (micronised purified flavonoid fraction – Daflon, diosmin), topical steroids or anaesthetics. If conservative therapy fails, rubber-band ligation or haemorrhoidectomy follow. If sea buckthorn suppositories were prescribed by a Russian doctor for a superficial anal fissure without active bleeding, the use follows the national pharmacopoeia. For overt bleeding, haemorrhoidal thrombosis or suspected colorectal cancer, sea buckthorn does not replace proctology assessment and colonoscopy.

ICD-10: K64 · ICD-11: DB60

Marketing claims without evidence base

The drug is promoted for these uses outside international guidelines. Each entry below is analyzed against AEMPS, FDA, EMA, Cochrane and major RCTs.

D

Superfoods and adaptogens (marketing category)

Not recommended

Sea buckthorn is marketed as a superfood and adaptogen, with claims that the berries and oil boost immunity, add energy and help the body handle stress. There's no solid evidence that sea buckthorn supplements do this. Sleep, regular activity and a balanced diet do more for energy and resilience; sea buckthorn itself is harmless as part of your diet.

How to read tiers A–F
  • AStrong evidence – first or second line in international guidelines
  • BRecommended in selected cases
  • CStudy data contradict each other
  • DBenefit not proven, no documented harm
  • FDocumented harm, or risk without benefit

Mechanism of action

Sea buckthorn is a thorny shrub whose berries contain carotenoids (beta-carotene, lycopene, zeaxanthin), vitamin C (up to 500 mg/100 g – more than orange), vitamin E, flavonoids (isorhamnetin, quercetin, kaempferol), omega-7 palmitoleic acid and omega-3 alpha-linolenic acid. Oil from berries and seeds applied to damaged skin and mucosa has antioxidant and anti-inflammatory effects in experimental burn and ulcer models. In humans it speeds epithelialisation of superficial wounds and first-to-second-degree burns in small studies. In Russia the Ministry of Health registers sea buckthorn oil as a medicinal product for topical use and as rectal suppositories. HMPC in 2021 granted sea buckthorn fruit traditional-herbal-medicinal-product status. in 2011 rejected oral sea buckthorn health claims for «general health» and immunity.

Safety

Contraindications

  • Known hypersensitivity to sea buckthorn berries or oil components
  • Acute cholecystitis or active gallstone disease (oral use)
  • Acute pancreatitis (oral use)
  • Diarrhoea (oral use – oil increases peristalsis)

Serious adverse effects

  • Severe allergic reactions in sea buckthorn-sensitised users (rare)

Common adverse effects

  • Yellowish skin discolouration with prolonged high-dose oral use (carotenodermia)
  • Gastrointestinal discomfort and diarrhoea with oral oil
  • Local irritation or burning on application to damaged skin
  • Orange staining of clothes and linen

Pregnancy: can you take Sea buckthorn?

Topical sea buckthorn oil on a small area in pregnancy is considered safe – systemic absorption is minimal. Oral sea buckthorn extracts and supplements have not been studied in pregnancy RCTs. EFSA has set no safe dose for pregnant women. AEMPS and AESAN advise against oral supplements without therapeutic indication during pregnancy.

Breastfeeding: can you take Sea buckthorn?

Topical sea buckthorn oil on the skin is compatible with lactation. Oral extracts have not been studied in nursing RCTs and are not justified.

Reference information, not a clinical decision. Discuss feeding pauses or changes with your physician or an IBCLC.

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Frequently asked

What is Sea buckthorn used for?

Sea buckthorn is evaluated for the following indications with varying evidence strength: Local burn and damaged-skin care (evidence tier C), Superfoods and adaptogens (marketing category) (evidence tier D), Hemorrhoidal disease (evidence tier D). See the full indication matrix with dosing and citations above on this page.

What are the side effects of Sea buckthorn?

Common side effects of Sea buckthorn (≥ 1 in 100): Yellowish skin discolouration with prolonged high-dose oral use (carotenodermia), Gastrointestinal discomfort and diarrhoea with oral oil, Local irritation or burning on application to damaged skin, Orange staining of clothes and linen. See the Safety section for uncommon and serious reactions.

Is Sea buckthorn safe during pregnancy?

Topical sea buckthorn oil on a small area in pregnancy is considered safe – systemic absorption is minimal. Oral sea buckthorn extracts and supplements have not been studied in pregnancy RCTs. EFSA has set no safe dose for pregnant women. AEMPS and AESAN advise against oral supplements without therapeutic indication during pregnancy.

Is Sea buckthorn compatible with breastfeeding?

Topical sea buckthorn oil on the skin is compatible with lactation. Oral extracts have not been studied in nursing RCTs and are not justified.

Who should not take Sea buckthorn?

Sea buckthorn is contraindicated in: Known hypersensitivity to sea buckthorn berries or oil components; Acute cholecystitis or active gallstone disease (oral use); Acute pancreatitis (oral use); Diarrhoea (oral use – oil increases peristalsis). Full list in the Safety section.

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