Evigrade

Silicon (organic silicon, silica from horsetail or bamboo)

Mineral in supplement form. Not registered as medicine in EU or AEMPS

ATC code: A11JA-SILICA

Brand names – supplements: Now Silica Complex, Solgar Silica, Nature's Way Silica Gel, BioSil ch-OSASupplements are not tested in clinical trials and are not registered as medications.

Updated · Methodology

Marketing claims without evidence base

The drug is promoted for these uses outside international guidelines. Each entry below is analyzed against AEMPS, FDA, EMA, Cochrane and major RCTs.

D

Age-related skin changes (wrinkles, elasticity)

Not recommended

Silicon and Silicium G5 are sold in Spain and France as «anti-aging skin products». 2009 approved no silicon claim for skin elasticity or connective tissue status. Barel 2005 RCT (n=50) showed moderate skin roughness and elasticity improvement with ch-OSA × 20 weeks, not reproduced in independent studies. Proven photoaging interventions are topical retinoids (tretinoin, adapalene), SPF 30+ sun protection and topical antioxidants (topical vitamin C). If silicon was recommended as a substitute for sun protection and topical retinoids, consider seeking a second opinion from a dermatologist.

D

Anti-aging and longevity

Not recommended

Silicon as organic silicon (horsetail or bamboo extract) is sold as a supplement to slow aging and support longevity, usually for skin, hair, and nails. The benefit for this use has not been shown: there is no solid evidence that it affects aging or lifespan. For skin and overall health, other approaches help – sun protection, not smoking, sleep, and a reasonable diet; for brittle hair or nails it makes sense to look for the specific cause with a doctor.

D

Skin, hair and nail beauty

Not recommended

Silicon is mass-marketed as a «product for hair, nails and skin» promising «collagen synthesis stimulation». 2009 reviewed manufacturer health claim applications for silicon on collagen synthesis and skin, hair and nail status: none approved. Several small RCTs (Wickett 2007, Barel 2005) showed moderate improvements in skin elasticity and nail strength with ch-OSA (choline-stabilised orthosilicic acid) 10 mg/day × 5–9 months; sample sizes around 50, not reproduced in independent groups. For diffuse hair loss 2024 lists workup (ferritin, TSH, testosterone, zinc) and treating the underlying cause; silicon supplements are not in the guideline. If silicon was recommended for marked hair loss or nail brittleness without workup, consider seeking a second opinion.

How to read tiers A–F
  • AStrong evidence – first or second line in international guidelines
  • BRecommended in selected cases
  • CStudy data contradict each other
  • DBenefit not proven, no documented harm
  • FDocumented harm, or risk without benefit

Mechanism of action

Silicon is a trace element present in connective tissue, cartilage, bone, skin, hair and nails. The bioactive form is orthosilicic acid. Dietary silicon comes from grains, vegetables, drinking water and beer. In skin and bone it participates in glycosaminoglycan synthesis and collagen fibre cross-linking. Supplement forms use horsetail (Equisetum arvense), bamboo (Bambusa vulgaris) or Silicium G5 (organic silicon). 2009 reviewed health claim applications for silicon on collagen synthesis, skin, hair and nail status: none approved due to lack of cause-effect evidence.

Safety

Contraindications

  • Hypersensitivity to extract components (horsetail, bamboo)
  • Pregnancy and lactation (for high-dose horsetail extracts only)
  • Children under 12 (for horsetail extracts)
  • Severe chronic kidney disease (silicon accumulation risk)

Serious adverse effects

  • Thiamine (B1) deficiency on long-term high-dose horsetail extracts
  • Allergic reactions up to anaphylaxis (rare)
  • Silicate-type nephrolithiasis at very high doses

Common adverse effects

  • Gastrointestinal discomfort
  • Nausea
  • Allergic skin reactions

Pregnancy: can you take Silicon (organic silicon, silica from horsetail or bamboo)?

No RCT data in pregnancy. Dietary silicon is safe at any gestational age. High-dose horsetail extract supplements contain thiaminase and palustrine alkaloids; avoid in pregnancy. AEMPS does not register as medicine.

Breastfeeding: can you take Silicon (organic silicon, silica from horsetail or bamboo)?

No data on milk transfer. Dietary silicon is safe. Avoid high-dose horsetail extracts during lactation.

Reference information, not a clinical decision. Discuss feeding pauses or changes with your physician or an IBCLC.

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Frequently asked

What is Silicon (organic silicon, silica from horsetail or bamboo) used for?

Silicon (organic silicon, silica from horsetail or bamboo) is evaluated for the following indications with varying evidence strength: Skin, hair and nail beauty (evidence tier D), Age-related skin changes (wrinkles, elasticity) (evidence tier D), Anti-aging and longevity (evidence tier D). See the full indication matrix with dosing and citations above on this page.

What are the side effects of Silicon (organic silicon, silica from horsetail or bamboo)?

Common side effects of Silicon (organic silicon, silica from horsetail or bamboo) (≥ 1 in 100): Gastrointestinal discomfort, Nausea, Allergic skin reactions. See the Safety section for uncommon and serious reactions.

Is Silicon (organic silicon, silica from horsetail or bamboo) safe during pregnancy?

No RCT data in pregnancy. Dietary silicon is safe at any gestational age. High-dose horsetail extract supplements contain thiaminase and palustrine alkaloids; avoid in pregnancy. AEMPS does not register as medicine.

Is Silicon (organic silicon, silica from horsetail or bamboo) compatible with breastfeeding?

No data on milk transfer. Dietary silicon is safe. Avoid high-dose horsetail extracts during lactation.

Who should not take Silicon (organic silicon, silica from horsetail or bamboo)?

Silicon (organic silicon, silica from horsetail or bamboo) is contraindicated in: Hypersensitivity to extract components (horsetail, bamboo); Pregnancy and lactation (for high-dose horsetail extracts only); Children under 12 (for horsetail extracts); Severe chronic kidney disease (silicon accumulation risk). Full list in the Safety section.

Other drugs in this group

Spermidine, Spirulina, Sulforaphane (isothiocyanate from broccoli sprouts), Thiamine, Andrographis paniculata, Cordyceps (Cordyceps sinensis, Cordyceps militaris), Lutein, Pyrroloquinoline quinone (PQQ)