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Antibodies to S-100 brain-specific protein (homeopathic)

Homeopathic products (local classification)

ATC code: V03AX-TENOTEN (Tenoten (homeopathic, local code))

Mechanism of action

The manufacturer claims 'release-active' antibodies to the S-100 protein in homeopathic dilutions C12, C30, C50. The concentration of active substance corresponds to less than one molecule per therapeutic dose. By the laws of physics and chemistry, substances at these dilutions are absent. The described mechanism does not match modern molecular pharmacology. The Australia 2015 systematic review of homeopathy concluded that 'there is no reliable evidence of efficacy for any clinical condition'.

Indications

F

ADHD

Not recommended

'Children's Tenoten' is advertised for 'concentration and attention in schoolchildren', effectively approaching ADHD-like marketing in manufacturer descriptions. International ADHD guidelines ( 2019, NG87) do not include homeopathic remedies. Prescribing Tenoten instead of proven therapy delays real care.

F

Anxiety and stress in children (marketed indication)

Not recommended

For treatment of clinically significant anxiety in children, international guidelines (AACAP 2020) list CBT and, in severe forms, SSRIs under paediatric psychiatric supervision. Prescribing homeopathy delays real care and maintains a false parental perception of ongoing treatment.

F

Generalized anxiety disorder

Not recommended

For anxiety disorder treatment, international guidelines ( 2023, CG113, WFSBP) list SSRIs, SNRIs, and CBT. Homeopathic remedies are absent from these documents. Cochrane reviews of homeopathy for anxiety have not found reliable evidence of efficacy.

F

Insomnia

Not recommended

Tenoten is positioned as a gentle sedative and 'sleep aid' for children and adults. For clinically significant insomnia, 2021 and CG193 recommend CBT-I and, if needed, melatonin agonists or orexin antagonists. Homeopathic remedies are not included.

Practical notes

homeopathy_position

International scientific consensus: homeopathy is treatment with 'nothing'. Australia (2015), Swiss HTA (2006), and (2017) independently concluded that there is no clinical efficacy. The homeopathic principle of 'like cures like' at dilutions where the original substance is physically absent is incompatible with biochemistry and pharmacology.

Common myths

Myth: 'Tenoten is safe because it is homeopathy, at worst a placebo, no harm done'. Fact: homeopathic products are as safe as a sugar pill. But when a child or adult with an actual anxiety disorder receives Tenoten instead of seeing a therapist or getting an SSRI, that is missed care. The harm is indirect – delayed treatment and condition progression.

Safety

Contraindications

  • Hypersensitivity to any component
  • Age under 3 years (for adult formulation)
  • Lactase deficiency, lactose intolerance, glucose-galactose malabsorption

Serious adverse effects

  • Direct serious adverse events are unlikely due to absence of active substance
  • The clinically meaningful risk is delayed treatment of actual psychiatric disorders

Common adverse effects

  • Per manufacturer label: rare allergic reactions

Pregnancy

Pregnancy safety data are limited. International sources do not recommend homeopathic products for any condition.

Frequently asked

What is Antibodies to S-100 brain-specific protein (homeopathic) used for?

Antibodies to S-100 brain-specific protein (homeopathic) is evaluated for the following indications with varying evidence strength: Generalized anxiety disorder (evidence tier F), Anxiety and stress in children (marketed indication) (evidence tier F), Insomnia (evidence tier F). See the full indication matrix with dosing and citations above on this page.

What are the side effects of Antibodies to S-100 brain-specific protein (homeopathic)?

Common side effects of Antibodies to S-100 brain-specific protein (homeopathic) (≥ 1 in 100): Per manufacturer label: rare allergic reactions. See the Safety section for uncommon and serious reactions.

Is Antibodies to S-100 brain-specific protein (homeopathic) safe during pregnancy?

Pregnancy safety data are limited. International sources do not recommend homeopathic products for any condition.

Who should not take Antibodies to S-100 brain-specific protein (homeopathic)?

Antibodies to S-100 brain-specific protein (homeopathic) is contraindicated in: Hypersensitivity to any component; Age under 3 years (for adult formulation); Lactase deficiency, lactose intolerance, glucose-galactose malabsorption. Full list in the Safety section.

Tenoten is safe because it is homeopathy, at worst a placebo, no harm done

homeopathic products are as safe as a sugar pill. But when a child or adult with an actual anxiety disorder receives Tenoten instead of seeing a therapist or getting an SSRI, that is missed care. The harm is indirect – delayed treatment and condition progression.

Reviewed: 4/26/2026

Updated: 4/26/2026