Inactivated viral vaccine
Updated · Methodology
First line
Hepatitis A during breastfeeding. CDC ACIP 2024 and SEGO 2023 – fully compatible. Particularly indicated for travel to endemic regions or exposure contact.
Sources
ICD-10: Z23 · ICD-11: QC00
Contains formalin-inactivated hepatitis A virus (strains HM175 or CR326F). Adjuvant – aluminum salts. Two doses (0 and 6–12 months) achieve protective titers in 99% and lifelong immunity.
Use when indicated. Safe.
Fully compatible. Hale L1.
Reference information, not a clinical decision. Discuss feeding pauses or changes with your physician or an IBCLC.
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Hepatitis A vaccine, inactivated is evaluated for the following indications with varying evidence strength: Vaccination during breastfeeding (evidence tier A). See the full indication matrix with dosing and citations above on this page.
Common side effects of Hepatitis A vaccine, inactivated (≥ 1 in 100): Injection-site pain, Fatigue, Headache. See the Safety section for uncommon and serious reactions.
Use when indicated. Safe.
Fully compatible. Hale L1.
Hepatitis A vaccine, inactivated is contraindicated in: Anaphylaxis to components; Acute febrile illness. Full list in the Safety section.
Hepatitis B vaccine, recombinant, HPV vaccine, nonavalent, Inactivated influenza vaccine, MMR – measles, mumps, rubella vaccine (live), RSV vaccine, recombinant (maternal), COVID-19 vaccine, mRNA (Moderna), Pneumococcal conjugate vaccine PCV20, Tdap – tetanus, diphtheria, acellular pertussis vaccine