Pantothenic acid

Pantothenic acid in high doses (5–10 g/day) is marketed as an «acne treatment» based on a single uncontrolled publication (Leung 1995). The 2015 Cochrane review of complementary acne therapies found no high-quality RCTs supporting efficacy. AEDV 2021 does not mention pantothenic acid in its acne guideline; first-line is topical retinoids and azelaic acid, doxycycline for moderate disease, isotretinoin for severe. High-dose B5 causes diarrhoea and does not outperform placebo. If pantothenic acid was prescribed for acne, consider seeking a second opinion: a dermatologist for an evidence-based regimen.

ICD-10: L70.0 · ICD-11: ED80

Pantothenic acid (vitamin B5) is added to supplements and marketed for fatigue and a boost of energy. In people without a deficiency (which is very rare), supplements have not shown convincing benefit for tiredness or low energy, and there is no evidence base for this use. Persistent fatigue responds to something else: find the cause (poor sleep, low iron, anemia, thyroid problems) and address it with a doctor.

ICD-10: R53 · ICD-11: MG22

Pantothenic acid (vitamin B5) is a water-soluble vitamin involved in metabolism. Supplements market it for glowing skin, hair growth, and stronger nails. No convincing benefit has been shown for this use: deficiency is rare on a normal diet, and extra intake does not improve skin, hair, or nails. Skin appearance responds to good skincare and sun protection; for hair loss or brittle nails, a dermatologist can find the cause – such as iron deficiency, a thyroid problem, or a skin condition – and treat it. The vitamin is harmless in this role, but do not take it instead of treatment with proven benefit, since that can mean missing the care you actually need.