Alcohol Denat.

Ethyl alcohol with denaturing additives. Quickly degreases the skin and creates a refreshing sensation. At high concentrations, it damages the lipid barrier and increases TEWL.

Evidence by route

Topical application

Weak evidence. In vitro data, open-label studies, or expert consensus.

Not an active ingredient but a solvent. Studies show dose-dependent lipid barrier damage and increased TEWL. No therapeutic value as a standalone treatment. At low concentrations (as a formula solvent), it is safe.

Lachenmeier DW. Regul Toxicol Pharmacol. 2008;50(2):218-228.

Tolerability and safety

Irritation potential

High

Allergen risk

Low

Pregnancy

Safe

For sensitive skin

At concentrations above 10% (high on the ingredient list), it can compromise barrier function. In sunscreens, it evaporates quickly and harm is minimal.

Skin types

Use with caution

SensitiveDry

Frequently asked questions

Is Alcohol Denat. safe during pregnancy?

Alcohol Denat. is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is Alcohol Denat. for?

Use with caution in: sensitive, dry.

Can Alcohol Denat. irritate the skin?

Yes, Alcohol Denat. has high irritation potential. Start at low concentrations, introduce gradually, and always use SPF during the day.