Broad-spectrum preservative, often used with benzyl alcohol. Works at pH below 6 and pairs well with natural formulas.
Topical application
CWeak evidence. In vitro data, open-label studies, or expert consensus.
Approved in the EU at concentrations up to 0.6%. Rarely irritating and suitable for minimalist paraben-free formulas.
Dehydroacetic Acid is a pyronone-derived broad-spectrum preservative. Often used together with benzyl alcohol (Dehydroacetic Acid + Benzyl Alcohol – Lonza's Geogard 221, one of the main 'natural' preservatives in cosmetics). Mechanism. Suppresses growth of gram-positive and gram-negative bacteria, yeasts, and molds. Acts by disrupting membrane transport in microorganisms and suppressing glycolytic enzymes. Effective at pH below 6. Where applied. Creams, lotions, shampoos, masks, especially in 'natural preservatives' and 'paraben-free' formulas. In Spain – niche eco brands (Freshly Cosmetics, Naturisimo), in Mercadona Deliplus 'clean beauty' lines. Evidence base. ISO 11930 challenge tests confirm dehydroacetic acid + benzyl alcohol efficacy in a standard preservation system. Weaker than classic preservatives (methylparaben, phenoxyethanol) but sufficient for low-microbial-risk formulas. Safety. CIR confirmed Dehydroacetic Acid safe up to 0.6% in cosmetics. SCCS in 2020 confirmed safety for leave-on and rinse-off products up to 0.6%. Irritation rare. Allergic contact dermatitis has been reported but is less common than with methylisothiazolinone. Pregnancy and lactation – safe at standard cosmetic concentrations. Best suited to: any skin type. A solid compromise for patients who avoid parabens and formaldehyde releasers.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
The Evigrade extension adds an evidence panel to Wildberries, Goldapple, Letu, iHerb, Sephora and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Dehydroacetic Acid is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Dehydroacetic Acid suits: oily, dry, sensitive, combination, normal.
Broad-spectrum preservative, often used with benzyl alcohol.
The INCI name is Dehydroacetic Acid.
Published: · updated: