Ester of isopropanol and adipic acid – a lightweight liquid emollient. Gives quick absorption and improves the spread of sunscreens and creams. Non-comedogenic and pregnancy-safe.
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
Functional emollient-solubilizer. Safety confirmed by CIR. No active effects.
Diisopropyl Adipate is a diester of isopropyl alcohol and adipic acid. INCI: Diisopropyl Adipate. It is produced by esterifying adipic acid with isopropanol over an acidic catalyst. A colorless oily liquid with very low viscosity. In cosmetics it works as a dry emollient and solubilizer. It dissolves oil-soluble UV filters (avobenzone, octocrylene) and crystalline actives. It gives quick absorption without a greasy film – convenient for sunscreens, BB creams and primers. Use levels run from 2 to 20%. Pregnancy safety. Skin absorption into the systemic circulation is minimal. CIR rates the safety profile as acceptable. No teratogenic effects are described. Skin profile. Low irritation and allergen potential. Comedogenicity on the rabbit-ear model is 0-1, not clinically relevant in real skin. Suitable for normal, combination and oily skin. For very dry skin it is better to combine it with heavier emollients – DIA alone does not seal the barrier. There are no active effects – it is a working solvent and sensorial modifier.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
The Evigrade extension adds an evidence panel to Wildberries, Goldapple, Letu, iHerb, Sephora and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Diisopropyl Adipate is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Diisopropyl Adipate suits: normal, combination, oily.
Ester of isopropanol and adipic acid – a lightweight liquid emollient.
On the Fulton scale 1/5 – very low comedogenicity. For acne-prone skin, a rating of 3 or higher suggests choosing an alternative.
The INCI name is Diisopropyl Adipate. It may also appear as: DIA, Диизопропил адипат.
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