Evigrade

Diisopropyl Sebacate

Ester of isopropanol and sebacic acid. A very lightweight emollient with dry slip, substitutes cyclomethicone in clean formulas. Non-comedogenic and pregnancy-safe.

Supporting ingredient

It gives a product its texture, stability or shelf life. It has no claimed effect on the skin, so an efficacy tier does not apply. What is known about its safety is below

Tolerability and safety

Irritation potential
Low
Allergen risk
Low
Pregnancy
Safe
Suitable for
Normal, Combination, Oily

About this ingredient

Diisopropyl Sebacate is a diester of isopropyl alcohol and sebacic acid (C10). INCI: Diisopropyl Sebacate. A colorless oily liquid with very low viscosity and a dry sensorial profile. It is often used as a replacement for cyclomethicone D5 in formulas positioned as silicone-free. In cosmetics it works as a solvent for oil-soluble actives and UV filters, and as a sensorial modifier. It reduces the viscosity of heavier oils and gives quick absorption. Use levels run from 2 to 25%; in sunscreens up to 30% as part of the oil phase. Pregnancy safety. Skin absorption into the systemic circulation is minimal. CIR rates the safety profile as acceptable. Skin profile. Low irritation and allergen potential. Non-comedogenic. Suitable for normal, combination and oily skin. On very dry skin without support from heavier emollients it may leave a feeling of tightness. There are no active effects.

Frequently asked questions

Is Diisopropyl Sebacate safe during pregnancy?

Diisopropyl Sebacate is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is Diisopropyl Sebacate for?

Diisopropyl Sebacate suits: normal, combination, oily.

What is Diisopropyl Sebacate and what does it do in cosmetics?

Ester of isopropanol and sebacic acid.

Is Diisopropyl Sebacate comedogenic?

On the Fulton scale 0/5 – non-comedogenic. For acne-prone skin, a rating of 3 or higher suggests choosing an alternative.

What's the INCI name for Diisopropyl Sebacate?

The INCI name is Diisopropyl Sebacate. It may also appear as: DIS.

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