Evigrade

Hexyl Cinnamal

Synthetic fragrance ingredient with a jasmine note. On the EU list of 26 fragrance allergens.

Evidence by route

C

Topical application

One of the most frequent components in fragrance mixes. Sensitization risk on prolonged contact.

How to read tiers A–F
  • CWeak evidence. In vitro data, open-label studies, or expert consensus

Tolerability and safety

Irritation potential
Medium
Allergen risk
High
Pregnancy
Caution
Suitable for
Normal, Dry, Oily, Combination
Use with caution
Sensitive

About this ingredient

Hexyl Cinnamal (HCA) is a synthetic aromatic aldehyde with a jasmine- and lily-like floral scent, produced by chemical synthesis from cinnamaldehyde. Used in perfumery and cosmetics as a fragrance component in toners, lotions, creams, soaps, shampoos, perfumes, and household products. Listed among the 26 EU mandatory disclosed cosmetic allergens (Annex III, Regulation 1223/2009): at >0.001% in leave-on and >0.01% in rinse-off products, it must appear by INCI on the label. SCCS pharmacovigilance data show that hexyl cinnamal causes allergic contact dermatitis in 0.5–2% of the general population and up to 5% of atopic dermatitis patients. Reactions typically present as itching, erythema, and vesicles at the application site. Not classified as phototoxic or as an endocrine disruptor. Patients with sensitive skin, atopic dermatitis, eczema, or prior contact dermatitis should look for 'Hexyl Cinnamal' on labels and avoid products containing it. Alternatives are fragrance-free formulations or products labeled as free from fragrance allergens.

Frequently asked questions

Is Hexyl Cinnamal safe during pregnancy?

Hexyl Cinnamal should be used with caution during pregnancy. Consulting a dermatologist or OB-GYN is advisable.

What skin types is Hexyl Cinnamal for?

Hexyl Cinnamal suits: normal, dry, oily, combination. Use with caution in: sensitive.

Can Hexyl Cinnamal irritate the skin?

Hexyl Cinnamal has moderate irritation potential. Sensitive skin may show a transient reaction that usually settles with adaptation.

Can Hexyl Cinnamal cause an allergic reaction?

Hexyl Cinnamal has high allergen potential. Perform a patch test on the inner forearm 24 hours before facial application.

What is Hexyl Cinnamal and what does it do in cosmetics?

Synthetic fragrance ingredient with a jasmine note.

What's the INCI name for Hexyl Cinnamal?

The INCI name is Hexyl Cinnamal. It may also appear as: Hexylcinnamaldehyde.

See Hexyl Cinnamal in a product composition right on the store page

The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.

Install the extension for free

Similar in action

Published: · updated: