INCI: Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde
Synthetic fragrance ingredient with a lily-of-the-valley scent. Banned in EU cosmetics since August 2021 due to high sensitization.
Topical application
DVery weak or conflicting data.
One of the strongest fragrance sensitizers per SCCS. EU fully removed it from cosmetics, international brands switched to substitutes.
HICC (Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde, Lyral) is a synthetic fragrance ingredient with a lily-of-the-valley scent, developed by IFF in the 1960s. EU ban. SCCS 2011 (Opinion 1456/11) based on patch-test data in 1.5-3% of patients with suspected fragrance allergy classified HICC as a strong sensitizer. EU Regulation 2017/1410 banned its use in cosmetics from August 2021 – the only fragrance ingredient fully banned. Where used (historically). Perfumery, soap, hair products with lily-of-the-valley scent (Dior J'adore, many classic feminine fragrances). After the ban brands reformulated. Safety. Banned in EU. Patch-test reactions in 1.5-3% of patients with suspected fragrance allergy. Pregnancy and lactation – avoid (AVOID).
Irritation potential
HighAllergen risk
HighPregnancy
AvoidUse with caution
The Evigrade extension adds an evidence panel to Wildberries, Goldapple, Letu, iHerb, Sephora and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
HICC (Lyral) is not recommended during pregnancy. Consider an alternative from the same category.
Use with caution in: sensitive, normal, dry, oily, combination.
Yes, HICC (Lyral) has high irritation potential. Start at low concentrations, introduce gradually, and always use SPF during the day.
HICC (Lyral) has high allergen potential. Perform a patch test on the inner forearm 24 hours before facial application.
Synthetic fragrance ingredient with a lily-of-the-valley scent.
Published: · updated:
The INCI name is Hydroxyisohexyl 3-Cyclohexene Carboxaldehyde. It may also appear as: HICC, Lyral.