Isoeugenol
Aromatic compound with a clove scent. Occurs in nutmeg oil and appears on the EU list of 26 fragrance allergens.
Evidence by route
Topical application
SCCS classes it as a strong sensitizer. EU strictly caps concentration in finished cosmetics at 0.02%.
How to read tiers A–F
- CWeak evidence. In vitro data, open-label studies, or expert consensus
Tolerability and safety
- Irritation potential
- Medium
- Allergen risk
- High
- Pregnancy
- Caution
- Suitable for
- Normal, Dry, Oily, Combination
- Use with caution
- Sensitive
About this ingredient
Isoeugenol is an aromatic substance with the scent of clove and nutmeg. A natural component of clove, nutmeg, ylang-ylang, and bergamot essential oils. Often synthesized for perfumery. Where applied. Perfumery, aromatic candles, household chemistry, floral-spicy notes in eaux de toilette, body balms. In Spain – Loewe, Carolina Herrera, Adolfo Dominguez, Puig (classic perfume houses). Allergenicity. On the EU list of 26 mandatory-labeled fragrance allergens (Annex III Regulation 1223/2009). IVDK data: one of the strongest sensitizers in perfumery. Sensitization in 1.5-3% of dermatitis patients. ESCD keeps isoeugenol in the standard patch-test panel. Safety. SCCS 2010 (Opinion 1295/10) limited isoeugenol in leave-on products to 0.02% (a full cosmetic ban was initially planned). No limit in rinse-off, but package labeling is required at >100 ppm. IFRA also set strict limits by use category. Pregnancy and lactation – topical use at cosmetic concentrations is acceptable, no direct teratogenicity data. With confirmed sensitization – avoid. Alternatives: fragrance-free formulas, hypoallergenic fragrance.
Frequently asked questions
Is Isoeugenol safe during pregnancy?
Isoeugenol should be used with caution during pregnancy. Consulting a dermatologist or OB-GYN is advisable.
What skin types is Isoeugenol for?
Isoeugenol suits: normal, dry, oily, combination. Use with caution in: sensitive.
Can Isoeugenol irritate the skin?
Isoeugenol has moderate irritation potential. Sensitive skin may show a transient reaction that usually settles with adaptation.
Can Isoeugenol cause an allergic reaction?
Isoeugenol has high allergen potential. Perform a patch test on the inner forearm 24 hours before facial application.
What is Isoeugenol and what does it do in cosmetics?
Aromatic compound with a clove scent.
What's the INCI name for Isoeugenol?
The INCI name is Isoeugenol.
See Isoeugenol in a product composition right on the store page
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