Branched five-carbon diol. Dissolves both oil- and water-soluble actives, boosts their penetration and acts as a mild preservative booster.
Topical application
CWeak evidence. In vitro data, open-label studies, or expert consensus.
Mild solvent with good tolerance. Penetration-booster effect is gentler than that of propylene glycol.
Isopentyldiol (3-Methyl-1,3-Butanediol) is a branched 5-carbon diol. Clear oily liquid without color or odor. Replaces heavier glycols (propylene glycol, butylene glycol) in modern formulas. Where applied. Solvent and solubilizer for fat- and water-soluble actives, fragrance carrier, mild preservative booster in creams, serums, toners, perfumes, deodorants (1-10%). Eases penetration of actives into the stratum corneum. In Spain in Sesderma C-Vit, Mesoestetic, Martiderm. Safety. CIR rated isopentyldiol safe at current cosmetic concentrations (2009). EU SCCS has set no restrictions. Irritation and sensitization are rare. Unlike propylene glycol – less pronounced irritation in patients with damaged barrier and atopic dermatitis. Pregnancy and lactation – safe topically. Suitable for all skin types.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
The Evigrade extension adds an evidence panel to Wildberries, Goldapple, Letu, iHerb, Sephora and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Isopentyldiol is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Isopentyldiol suits: normal, dry, oily, combination, sensitive.
Branched five-carbon diol.
The INCI name is Isopentyldiol. It may also appear as: Изопентилдиол.
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