Emollient from isopropyl alcohol and palmitic acid. Gives a dry slip but in acne-prone skin may worsen clogged pores.
Topical application
CWeak evidence. In vitro data, open-label studies, or expert consensus.
Safe on its own, but part of the literature shows moderate comedogenic potential. For oily skin formulas without this emollient on the first line are reasonable.
Isopropyl Palmitate (IPP) is a synthetic ester of isopropanol and palmitic acid (C16). Clear oily liquid with a light dry finish. Sibling of isopropyl myristate with a slightly longer chain. Where applied. Creams, lotions, body products, lipsticks, eyeshadows, shaving products, antiperspirants, pharmaceutical ointments (1-50%). Provides "dry" slip and improves product spreading. In Spain in Babaria, Mercadona Deliplus, Bioderma formulas, men's shaving products. Comedogenicity. Like isopropyl myristate, IPP gained a comedogenic reputation from early rabbit ear studies. On acne-prone skin it may worsen pore clogging – not critical, but with acne-prone facial skin prefer alternatives (squalane, capric/caprylic triglyceride). On body and in color cosmetics this is practically not an issue. Safety. CIR rated isopropyl palmitate safe at cosmetic concentrations (1982, re-evaluated 2018). EU SCCS has set no restrictions. Irritation and sensitization are rare. Pregnancy and lactation – safe topically. Suitable for dry and normal skin.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
Use with caution
The Evigrade extension adds an evidence panel to Wildberries, Goldapple, Letu, iHerb, Sephora and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Isopropyl Palmitate is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Isopropyl Palmitate suits: dry, normal. Use with caution in: oily, combination.
Emollient from isopropyl alcohol and palmitic acid.
On the Fulton scale 4/5 – high comedogenicity. For acne-prone skin, a rating of 3 or higher suggests choosing an alternative.
The INCI name is Isopropyl Palmitate. It may also appear as: Изопропил пальмитат.
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