Pantolactone
Lactone of pantothenic acid. Skin and hair conditioner related to panthenol, but without a pronounced clinical effect.
Supporting ingredient
It gives a product its texture, stability or shelf life. It has no claimed effect on the skin, so an efficacy tier does not apply. What is known about its safety is below
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Normal, Dry, Oily, Combination, Sensitive
About this ingredient
Pantolactone is the synthetic lactone form of pantothenic acid (vit B5). On skin it hydrolyzes to pantothenic acid – the active form. Mechanism. A pantothenic acid source with better stability and epidermal penetration. After penetration it is converted to coenzyme A – a key cofactor of cellular metabolism and lipid synthesis. Where applied. Repair serums and creams, burn and irritation products, hair products. Concentration 0.5–5%. Evidence base. Pantolactone clinical RCTs are few. The evidence base is closer to pantothenic acid and dexpanthenol. CIR confirmed safety. Safety. Hypoallergenic, non-comedogenic. Pregnancy and lactation – topically safe.
Frequently asked questions
Is Pantolactone safe during pregnancy?
Pantolactone is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Pantolactone for?
Pantolactone suits: normal, dry, oily, combination, sensitive.
What is Pantolactone and what does it do in cosmetics?
Lactone of pantothenic acid.
What's the INCI name for Pantolactone?
The INCI name is Pantolactone. It may also appear as: D-Pantolactone.
See Pantolactone in a product composition right on the store page
The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Similar role in the formula
Other functional ingredients
PCA Dimethicone, Pectin, PEG-10 Dimethicone, PEG-10 Isostearate, PPG-1-PEG-9 Lauryl Glycol Ether, TEA-Sulfate, Caprylic/Capric/Myristic/Stearic Triglyceride, Glycereth-2 Cocoate
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