W/O emulsifier from oleic acid and sorbitol. Known contact allergen in patients sensitive to lanolin.
Topical application
CWeak evidence. In vitro data, open-label studies, or expert consensus.
Emulsifier with documented contact allergy in some patients.
Sorbitan Sesquioleate is a non-ionic emulsifier ester of sorbitol and oleic acid. Known in dermatology as a contact allergen in some patients reactive to lanolin and in 'lanolin-sensitised' eczema. Mechanism. Stabilises water-in-oil emulsions and provides mild slip. Used mostly in rich creams and balms. Where applied. Pharmaceutical creams and ointments (Eucerin, Vichy Lipidiose), colour cosmetics, body products. Less common in face skincare. Safety. CIR confirmed safety at cosmetic concentrations but listed it as a contact allergen: 5-15% of lanolin-reactive patients also react to sorbitan sesquioleate (Hannuksela 1996). Non-comedogenic. Pregnancy and lactation – safe. Patients with confirmed lanolin-derivative allergy should avoid it.
Irritation potential
LowAllergen risk
ModeratePregnancy
SafeSuitable for
Use with caution
The Evigrade extension adds an evidence panel to Wildberries, Goldapple, Letu, iHerb, Sephora and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Sorbitan Sesquioleate is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Sorbitan Sesquioleate suits: normal, dry, oily, combination. Use with caution in: sensitive.
W/O emulsifier from oleic acid and sorbitol.
The INCI name is Sorbitan Sesquioleate.
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