Thiamine HCl
Hydrochloride salt of thiamine, vitamin B1. Rare in cosmetics, appears in multivitamin «cocktails» and masks. Topical action on skin is almost unstudied clinically; in formula serves as a marketing add-on.
Evidence by route
Topical application
Safety is confirmed, but no clinical data on topical efficacy support the claimed «energizing» effects.
- CIR Cosmetic Ingredient Review safety assessment.
How to read tiers A–F
- DNo data, or very weak or conflicting data
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Normal, Dry, Combination, Oily, Sensitive
About this ingredient
Thiamine HCl (vitamin B1) is a water-soluble B-vitamin. Orally used in beriberi, alcoholic neuropathy, CNS lesions. Rare in cosmetics. Mechanism. In skin cells it acts as a cofactor for pyruvate dehydrogenase and transketolase – enzymes of carbohydrate metabolism. Topical action is essentially unstudied, with no direct skin-efficacy data. Where applied. Multivitamin 'cocktails' in serums and masks, k-beauty products, marketing 'vitamin boost' formulations. Concentration below 0.5%. Evidence base. Clinical RCTs of topical thiamine for specific skin indications are not available. A marketing add-on – 'skin needs vitamins' – but vitamin B1 hardly penetrates intact stratum corneum. Safety. CIR confirmed safety. Contact reactions are rare. Patients with confirmed injectable thiamine allergy should avoid topical use. Pregnancy and lactation – safe topically.
Frequently asked questions
Is Thiamine HCl safe during pregnancy?
Thiamine HCl is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Thiamine HCl for?
Thiamine HCl suits: normal, dry, combination, oily, sensitive.
What is Thiamine HCl and what does it do in cosmetics?
Hydrochloride salt of thiamine, vitamin B1.
What's the INCI name for Thiamine HCl?
The INCI name is Thiamine HCl. It may also appear as: Thiamine Hydrochloride, Vitamin B1.
See Thiamine HCl in a product composition right on the store page
The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
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