Hydrochloride salt of thiamine, vitamin B1. Rare in cosmetics, appears in multivitamin «cocktails» and masks. Topical action on skin is almost unstudied clinically; in formula serves as a marketing add-on.
Topical application
DVery weak or conflicting data.
Safety is confirmed, but no clinical data on topical efficacy support the claimed «energizing» effects.
Thiamine HCl (vitamin B1) is a water-soluble B-vitamin. Orally used in beriberi, alcoholic neuropathy, CNS lesions. Rare in cosmetics. Mechanism. In skin cells it acts as a cofactor for pyruvate dehydrogenase and transketolase – enzymes of carbohydrate metabolism. Topical action is essentially unstudied, with no direct skin-efficacy data. Where applied. Multivitamin 'cocktails' in serums and masks, k-beauty products, marketing 'vitamin boost' formulations. Concentration below 0.5%. Evidence base. Clinical RCTs of topical thiamine for specific skin indications are not available. A marketing add-on – 'skin needs vitamins' – but vitamin B1 hardly penetrates intact stratum corneum. Safety. CIR confirmed safety. Contact reactions are rare. Patients with confirmed injectable thiamine allergy should avoid topical use. Pregnancy and lactation – safe topically.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
The Evigrade extension adds an evidence panel to Wildberries, Goldapple, Letu, iHerb, Sephora and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Thiamine HCl is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Thiamine HCl suits: normal, dry, combination, oily, sensitive.
Hydrochloride salt of thiamine, vitamin B1.
The INCI name is Thiamine HCl. It may also appear as: Thiamine Hydrochloride, Vitamin B1, Витамин B1.
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