MinorPsycholeptics. Lithium×Mineral supplements. Macrominerals
Updated · Methodology
Mechanism
Magnesium theoretically antagonises lithium-driven neuronal excitability, but no clinical cases of efficacy loss at standard magnesium doses (up to 400 mg/day) have been described.
Symptoms
The combination usually causes no specific symptoms. Each drug's individual side effects remain.
Management
No dose adjustment needed. On stable lithium dose, monitor levels on the usual schedule. Higher magnesium doses (over 1 g/day) are discussed separately — hypermagnesaemia risk in chronic kidney disease.
Check the full regimen, not just this pair
Opens the checker with these two drugs prefilled. Add the rest of the regimen and recompute additive risks.
Summary of a multi-drug list →
Medicine list: everything you take in one place →
Sources
- FDA: Lithium carbonate tablet (Glenmark Pharmaceuticals Inc., USA) – Prescribing Information (2005)– ; DailyMed setid 1b65d27e-5086-4a87-8387-c49f3d060978