Squalene
Unsaturated hydrocarbon and a natural sebum component. Unlike squalane, it is unstable and oxidizes rapidly, limiting its use in pure form.
Moisturizing
Evidence by route
Topical application
CWeak evidence. In vitro data, open-label studies, or expert consensus.
Emollient properties confirmed in small studies. Oxidized squalene can trigger comedogenesis, which is why formulas typically use stable squalane instead.
- Huang ZR et al. Molecules. 2009;14(1):540-554.
Tolerability and safety
Irritation potential
LowAllergen risk
LowPregnancy
SafeSkin types
Suitable for
DryNormalCombination
Use with caution
Oily
Frequently asked questions
Is Squalene safe during pregnancy?
Squalene is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Squalene for?
Squalene suits: dry, normal, combination. Use with caution in: oily.