NSAID gastropathy prophylaxis
Gastroprotection in patients on long-term NSAIDs with GI risk factors.
ICD-10 K312 drugs
Also known as: NSAID-induced gastropathy prevention
Drugs used for this condition
- AOmeprazoleFirst line · Proton pump inhibitorsGastroprotection is indicated in long-term NSAID users with risk factors: age over 65, prior peptic ulcer or GI bleeding, concomitant anticoagulants, antiplatelet drugs, or glucocorticoids, and high NSAID doses. Routine gastroprotection in low-risk patients is not recommended.
- APantoprazoleFirst line · Proton pump inhibitorsFirst-line prophylaxis of gastropathy in patients on long-term NSAIDs with risk factors – age over 65, ulcer history, concomitant anticoagulants or corticosteroids. Pantoprazole 20 mg once daily for the duration of NSAID therapy.
How to read tiers A–F
Evidence tiers belong to the drug-indication pair, not to the drug as a whole: the same substance can be A for one condition and F for another.
- AStrong evidence – first or second line in international guidelines
- BRecommended in selected cases
- CStudy data contradict each other
- DBenefit not proven, no documented harm
- FDocumented harm, or risk without benefit