Post-myocardial infarction heart failure

Heart failure developing after myocardial infarction. Valsartan proved effective as an alternative to captopril in the VALIANT trial.

ICD-10 I50.11 drug

Also known as: Post-MI HF, Post-infarction heart failure

Drugs used for this condition

BValsartanSecond line · Angiotensin II receptor blockers (ARBs)Valsartan is an alternative to captopril in post-MI heart failure. The VALIANT trial (over 14,000 patients) showed that valsartan 160 mg twice daily was as effective as captopril for mortality and cardiovascular events. Prescribed for patients who do not tolerate ACE inhibitors.

How to read tiers A–F

Evidence tiers belong to the drug-indication pair, not to the drug as a whole: the same substance can be A for one condition and F for another.

AStrong evidence – first or second line in international guidelines
BRecommended in selected cases
CStudy data contradict each other
DBenefit not proven, no documented harm
FDocumented harm, or risk without benefit