Post-MI left ventricular dysfunction

Reduced left ventricular systolic function after acute myocardial infarction. Early ACE inhibitors/ARBs, beta-blockers, and MRAs are indicated.

ICD-10 I25.51 drug

Also known as: LV dysfunction after MI

Drugs used for this condition

AEnalaprilFirst line · Angiotensin-converting enzyme inhibitors (ACEi)Early initiation of ACE inhibitors (within the first 24 h when hemodynamically stable) after myocardial infarction with reduced LVEF reduces mortality, reinfarction, and heart failure progression. Evidence from SAVE, AIRE, TRACE, and SOLVD trials.

How to read tiers A–F

Evidence tiers belong to the drug-indication pair, not to the drug as a whole: the same substance can be A for one condition and F for another.

AStrong evidence – first or second line in international guidelines
BRecommended in selected cases
CStudy data contradict each other
DBenefit not proven, no documented harm
FDocumented harm, or risk without benefit