Post-stroke recovery
Rehabilitation after ischaemic or haemorrhagic stroke. AHA/ASA and ESO guidelines list early mobilisation, physical and speech therapy as the foundation of recovery, not nootropic pharmacotherapy.
ICD-10 I694 drugs
Also known as: Stroke rehabilitation
Drugs used for this condition
Marketing claims without evidence base
The drug is promoted for these uses outside international guidelines. Each entry below is analyzed against AEMPS, FDA, EMA, Cochrane and major RCTs.
- FCortexin (bovine brain cortex polypeptides)Not recommended · Other psychostimulants and nootropics (local classification)Cortexin is not mentioned in AHA/ASA Stroke Rehabilitation Guidelines 2016 or ESO. Evidence-based rehabilitation rests on early mobilization, physical and occupational therapy, speech therapy, and psychological support. CIMT helps hemiparesis; intensive speech therapy helps dysphasia. Pharmacotherapy in rehabilitation is largely limited to antidepressants for post-stroke depression.
- FCytoflavin (succinic acid, nicotinamide, riboflavin, inosine complex)Not recommended · Other metabolic agents (local classification)In post-stroke rehabilitation, Cytoflavin is not mentioned in AHA/ASA Stroke Rehabilitation Guidelines 2016 or ESO. Effective approaches: early mobilization, physical and occupational therapy, speech therapy, psychological support. CIMT helps hemiparesis; intensive speech therapy helps dysphasia. Pharmacotherapy is largely limited to antidepressants for post-stroke depression.
- FPiracetamNot recommended · Old «nootropics» (local classification)Piracetam is not included in international stroke rehabilitation guidelines (AHA/ASA 2023, ESO 2022). Recovery relies on early mobilisation, physical, occupational, and speech therapy, and cardiovascular risk management.
How to read tiers A–F
Evidence tiers belong to the drug-indication pair, not to the drug as a whole: the same substance can be A for one condition and F for another.
- AStrong evidence – first or second line in international guidelines
- BRecommended in selected cases
- CStudy data contradict each other
- DBenefit not proven, no documented harm
- FDocumented harm, or risk without benefit