Routine tetanus, diphtheria and pertussis booster (adolescents and adults)

ICD-10 Z231 drug

Drugs used for this condition

ATdap – tetanus, diphtheria, acellular pertussis vaccineFirst line · Combined inactivated bacterial vaccine (Td + acellular pertussis)One Tdap dose for adolescents at 11–12 years, then a Td or Tdap booster every 10 years. Covers three infections at once: tetanus, diphtheria and pertussis. Per ACIP (MMWR 2020) and the Spanish AEP schedule, this is the standard way to maintain immunity in adolescents and adults, with no alternative.

How to read tiers A–F

Evidence tiers belong to the drug-indication pair, not to the drug as a whole: the same substance can be A for one condition and F for another.

AStrong evidence – first or second line in international guidelines
BRecommended in selected cases
CStudy data contradict each other
DBenefit not proven, no documented harm
FDocumented harm, or risk without benefit