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CHA₂DS₂-VA, thromboembolic risk in atrial fibrillation

The ESC 2024 version without the sex category: maximum 8 points. Anticoagulation is recommended from 2 points.

Updated · Methodology

ESC 2024 version. The scale has no sex category: the maximum is 8 points, not 9.

About this calculator

The 2024 ESC atrial fibrillation guidelines replaced CHA2DS2-VASc with CHA2DS2-VA by removing the sex category. The reasoning is that female sex acts as a risk modifier rather than an independent factor, and the threshold for anticoagulation does not depend on sex. A further argument named in the guideline text concerns people not described by a binary sex category. The remaining components are unchanged: heart failure 1 point, hypertension 1, age 65-74 one point and 75 or older two points, diabetes 1, stroke or TIA 2, vascular disease 1. The maximum is now 8 instead of 9. The threshold is unchanged: from 2 points anticoagulation is indicated, at 1 point the decision is individual. Worth keeping in mind: the score describes thromboembolic risk, not treatment benefit, and says nothing about which agent to choose. Bleeding risk is assessed separately, and a high HAS-BLED does not cancel anticoagulation but points at modifiable factors. The scale does not apply to atrial fibrillation with moderate or severe mitral stenosis or a mechanical valve prosthesis, where the valve lesion itself determines the indication for warfarin.

Source

Van Gelder IC, Rienstra M, Bunting KV et al. 2024 ESC Guidelines for the management of atrial fibrillation. Eur Heart J 2024;45(36):3314-3414.

Formula version: esc-2024-v1

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