ModerateBenzodiazepines. Short-to-medium-acting anxiolytics×Angiotensin II receptor blocker (ARB)
Updated · Methodology
Mechanism
Additive hypotension. Benzodiazepines have weak hypotensive effect; the main one comes from the ARB. In most patients, clinically minor.
Symptoms
Postural dizziness, syncope, fatigue. Older patients: fall and fracture risk. Morning weakness possible at standard doses.
Management
No dose adjustment usually needed. In older patients on starting telmisartan, check standing/sitting BP at one week. With pronounced morning hypotension, move alprazolam from night to morning or switch to buspirone.
Check the full regimen, not just this pair
Opens the checker with these two drugs prefilled. Add the rest of the regimen and recompute additive risks.
Summary of a multi-drug list →
Medicine list: everything you take in one place →
Sources
- FDA: Telmisartan tablet (Alembic Pharmaceuticals Limited) – Prescribing Information section 7 (2014)– ; DailyMed setid 4be6575f-ea8d-4cd8-a49d-3d1c93f2621a