MinorVitamins. Antioxidants×Biguanides. Oral antihyperglycemic agents
Updated · Methodology
Mechanism
No direct pharmacokinetic interaction. Vitamin C increases iron absorption, not metformin's.
Symptoms
The combination usually causes no specific symptoms. Each drug's individual side effects remain.
Management
No dose adjustment needed. In diabetics on metformin, ascorbic acid may improve plant-source iron absorption in patients with deficiency.
Check the full regimen, not just this pair
Opens the checker with these two drugs prefilled. Add the rest of the regimen and recompute additive risks.
Summary of a multi-drug list →
Medicine list: everything you take in one place →
Sources
- FDA: Metformin hydrochloride tablet (Sciegen Pharmaceuticals Inc) – Prescribing Information (2017)– ; DailyMed setid 4e4c4ba9-65c6-4273-8f6b-2423ab521dad