Evigrade
CriticalLong-acting organic nitrate×Phosphodiesterase type 5 (PDE-5) inhibitor

Updated · Methodology

Mechanism

Same pharmacodynamics – synergistic hypotension.

Symptoms

Fatal hypotension.

Management

Combination contraindicated. 24-hour washout.

Check the full regimen, not just this pair

Opens the checker with these two drugs prefilled. Add the rest of the regimen and recompute additive risks.

Open checker

Summary of a multi-drug list →

Medicine list: everything you take in one place →

Sources

Other interactions with Isosorbide mononitrate

Other interactions with Vardenafil