Minor
Metronidazole × Paracetamol
Imidazole derivatives (antiprotozoal / antibacterial)×Anilides. Analgesics and antipyretics
Mechanism
No direct pharmacokinetic interaction. Co-administration at standard doses is safe.
Symptoms
The combination usually causes no specific symptoms. Each drug's individual side effects remain.
Management
No dose adjustment needed. Paracetamol remains the analgesic and antipyretic of choice on metronidazole.
Check the full regimen, not just this pair
Opens the checker with these two drugs prefilled. Add the rest of the regimen and recompute additive risks.
Sources
- Lexicomp: Lexicomp Drug Interactions (2024)– Wolters Kluwer Clinical Drug Information, Inc. Lexi-Interact Online, 2024
- Pharmaceutical Press: Stockley's Drug Interactions, 12th edition (2024)– Preston CL (ed.). Stockley's Drug Interactions. 12th ed. London: Pharmaceutical Press; 2024