Evigrade

Medicines

Evidence-based reviews of medicines and drug classes: which indications have proven efficacy, which rest on weak trials, and what current guidelines advise

About this section

This section covers individual medicines and pharmacological classes through the lens of evidence-based medicine: clinical trials, systematic reviews, current international society guidelines, and Russian Ministry of Health clinical recommendations. Every article answers three questions: which indications have proven efficacy, which uses rely on outdated or low-quality evidence, and what alternatives current guidelines recommend. Drugs with marketing-driven indications unsupported by independent RCTs are flagged separately – many such drugs are sold for decades in Russia and the CIS while their clinical use is limited or absent in Europe and the United States.