Evigrade

Cosmetics

Cosmetic ingredients, routines and protocols graded by evidence: working concentrations, skin-type limits and marketing claims without clinical support

About this section

This section covers cosmetic formulations, active ingredients, and skincare protocols. Most industry claims of 'anti-aging,' 'restoring,' or 'nourishing' lack clinical proof – SCCS and FDA approval addresses safety, not efficacy. Full clinical evidence exists for a narrow set of compounds: retinoids and derivatives, niacinamide, azelaic acid, AHA/BHA acids, vitamin C, hyaluronic acid, ceramides, peptides, and SPF filters. Articles cover active ingredients by evidence level, working concentrations, restrictions by skin type and condition (rosacea, acne, sensitive skin, pregnancy), routine combinations and conflicts, and marketing pitfalls and claims without PubMed-indexed support.