Evigrade

Anhydroxylitol

Dehydrated form of xylitol, humectant. Often part of the Aquaxyl complex (with xylitol and xylitylglucoside).

Evidence by route

C

Topical application

Safe humectant sugar.

How to read tiers A–F
  • CWeak evidence. In vitro data, open-label studies, or expert consensus

Tolerability and safety

Irritation potential
Low
Allergen risk
Low
Pregnancy
Safe
Suitable for
Normal, Dry, Oily, Combination, Sensitive

About this ingredient

Anhydroxylitol is a dehydrated form of xylitol, a five-carbon sugar alcohol. A humectant included in the Aquaxyl complex by Solabia (xylitol + xylitylglucoside + anhydroxylitol). Mechanism. Binds water in the stratum corneum via multiple hydroxyl groups. Activates aquaporin (AQP-3) and hyaluronic acid synthesis in skin – a deep 'long-lasting' humectant effect. Within Aquaxyl it works synergistically with the other components. Where applied. Moisturizing serums and creams (1–3% as part of Aquaxyl, pure anhydroxylitol 0.5–2%), masks, anti-dehydration products. Brands: Sesderma Hidraderm Hyal, Mesoestetic, Filorga. Evidence base. Solabia (Aquaxyl manufacturer) has published in vitro and small clinical work – 30% increase in stratum corneum water content over 8 weeks of 3% Aquaxyl use. Few direct independent RCTs. Safety. CIR has not assessed it individually. Hypoallergenic, non-irritating, non-comedogenic. Pregnancy and lactation – safe. Acceptable at any stage. Functional role. A moisturizing humectant with a plausible mechanism. A standard add-on to hyaluronic acid and glycerin in anti-dehydration formulas.

Frequently asked questions

Is Anhydroxylitol safe during pregnancy?

Anhydroxylitol is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is Anhydroxylitol for?

Anhydroxylitol suits: normal, dry, oily, combination, sensitive.

What is Anhydroxylitol and what does it do in cosmetics?

Dehydrated form of xylitol, humectant.

What's the INCI name for Anhydroxylitol?

The INCI name is Anhydroxylitol.

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