Dehydrated form of xylitol, humectant. Often part of the Aquaxyl complex (with xylitol and xylitylglucoside).
Topical application
CWeak evidence. In vitro data, open-label studies, or expert consensus.
Safe humectant sugar.
Anhydroxylitol is a dehydrated form of xylitol, a five-carbon sugar alcohol. A humectant included in the Aquaxyl complex by Solabia (xylitol + xylitylglucoside + anhydroxylitol). Mechanism. Binds water in the stratum corneum via multiple hydroxyl groups. Activates aquaporin (AQP-3) and hyaluronic acid synthesis in skin – a deep 'long-lasting' humectant effect. Within Aquaxyl it works synergistically with the other components. Where applied. Moisturizing serums and creams (1–3% as part of Aquaxyl, pure anhydroxylitol 0.5–2%), masks, anti-dehydration products. Brands: Sesderma Hidraderm Hyal, Mesoestetic, Filorga. Evidence base. Solabia (Aquaxyl manufacturer) has published in vitro and small clinical work – 30% increase in stratum corneum water content over 8 weeks of 3% Aquaxyl use. Few direct independent RCTs. Safety. CIR has not assessed it individually. Hypoallergenic, non-irritating, non-comedogenic. Pregnancy and lactation – safe. Acceptable at any stage. Functional role. A moisturizing humectant with a plausible mechanism. A standard add-on to hyaluronic acid and glycerin in anti-dehydration formulas.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
The Evigrade extension adds an evidence panel to Wildberries, Goldapple, Letu, iHerb, Sephora and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Anhydroxylitol is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Anhydroxylitol suits: normal, dry, oily, combination, sensitive.
Dehydrated form of xylitol, humectant.
The INCI name is Anhydroxylitol.
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