Evigrade

C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate

An oil-soluble derivative of hyaluronic acid. It retains moisture and supports skin smoothness. Well tolerated.

Evidence by route

B

Topical application

A hydrating hyaluronate derivative. Safe.

  • CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
  • BLimited evidence. One RCT or several controlled studies with limitations

Tolerability and safety

Irritation potential
Low
Allergen risk
Low
Pregnancy
Safe
Suitable for
Normal, Dry, Combination, Oily, Sensitive

About this ingredient

C12-13 alkyl glyceryl hydrolyzed hyaluronate (INCI C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate) is a hyaluronic acid derivative modified with fatty chains to make it oil-soluble. That change lets it sit in the oil phase and come closer to the skin's lipid barrier. In a formula it acts as a humectant. On efficacy, it is a supporting component in hydration. It holds water like classic hyaluronate, with the advantage of being oil-soluble, which helps its spread in formulas containing oils. Data specific to this variant are limited, so it is realistic to expect good surface hydration. Applied topically it has no systemic relevance, so it can be used during pregnancy and breastfeeding. Tolerance is good, with low irritation and allergy potential, suitable for sensitive skin. Already-sensitized people may see an occasional reaction, though most do not.

Frequently asked questions

Is C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate safe during pregnancy?

C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate for?

C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate suits: normal, dry, combination, oily, sensitive.

What is C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate and what does it do in cosmetics?

An oil-soluble derivative of hyaluronic acid.

What's the INCI name for C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate?

The INCI name is C12-13 Alkyl Glyceryl Hydrolyzed Hyaluronate.

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