Evigrade

C12-16 Alcohols

Blend of medium-chain fatty alcohols. Does NOT dry the skin: fatty alcohols act as emollients and co-emulsifiers, unlike ethanol.

Evidence by route

B

Topical application

Fatty alcohols with C12-16 chain. Well tolerated, typical emollient in creams. Not to be confused with short-chain alcohols (ethanol, isopropyl) which may dry the skin.

  • CIR Expert Panel. Int J Toxicol. 1988;7(3):359-413.
How to read tiers A–F
  • BLimited evidence. One RCT or several controlled studies with limitations

Tolerability and safety

Irritation potential
Low
Allergen risk
Low
Pregnancy
Safe
Suitable for
Normal, Dry, Oily, Combination, Sensitive

About this ingredient

C12-16 Alcohols are a mid-length fatty alcohol blend (lauryl C12, myristyl C14, cetyl C16). Usually plant-derived from coconut and palm oil. Not to be confused with ethanol and short-chain alcohols that dry the skin. Mechanism. On skin they work as softening emollients and co-emulsifiers. The long lipophilic chain embeds into intercellular stratum corneum lipids and reinforces the barrier. In formula they give creams a dense pleasant texture and stabilise emulsions. Where applied. Creams, lotions, hair conditioners, shampoos (as foam aids), shaving products, lipsticks. Concentration 1–10%. In Spain in La Roche-Posay Toleriane, Avène Cold Cream, ISDIN, Bioderma. Safety. CIR confirmed safety of the C12-C22 fatty alcohol family in cosmetics in 2018. Hypoallergenic, non-comedogenic (despite lauryl alcohol content – in a blended form comedogenicity is low). Irritation and contact allergy are isolated. Pregnancy and lactation – safe. Used without restriction. A common misconception. Many users confuse C12-C22 fatty alcohols with ethanol ('alcohol denat.', 'alcohol') and fear a drying effect. In fact, fatty alcohols do not dry – they soften and support the barrier. 'Cetyl Alcohol', 'Cetearyl Alcohol', 'Lauryl Alcohol', 'C12-16 Alcohols' on a label are emollients, not drying agents. Functional role. Formula emollients and co-emulsifiers. No standalone activity as a cosmetic active.

Frequently asked questions

Is C12-16 Alcohols safe during pregnancy?

C12-16 Alcohols is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is C12-16 Alcohols for?

C12-16 Alcohols suits: normal, dry, oily, combination, sensitive.

What is C12-16 Alcohols and what does it do in cosmetics?

Blend of medium-chain fatty alcohols.

What's the INCI name for C12-16 Alcohols?

The INCI name is C12-16 Alcohols. It may also appear as: C12-16 Alcohol.

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