Evigrade

Caprylyl Glycol

Multifunctional ingredient that boosts preservatives and works as a mild humectant and conditioner. Often paired with phenoxyethanol.

Evidence by route

C

Topical application

Formulation aid. The CIR expert panel confirmed safety at cosmetic concentrations. No standalone therapeutic effect.

How to read tiers A–F
  • CWeak evidence. In vitro data, open-label studies, or expert consensus

Tolerability and safety

Irritation potential
Low
Allergen risk
Low
Pregnancy
Safe
Suitable for
Oily, Dry, Sensitive, Combination, Normal

About this ingredient

Caprylyl Glycol (1,2-octanediol) is a multifunctional cosmetic ingredient. It acts simultaneously as a mild humectant, skin and hair conditioner, and preservative booster. Produced synthetically or from plant sources (coconut, palm kernel). Mechanism. A humectant with light lipophilic affinity – retains moisture in the stratum corneum while penetrating lipids. Antimicrobial effect – disrupts the membrane of gram-positive and gram-negative bacteria and fungi. Not a stand-alone preservative (not on the EU 1223/2009 approved list) but boosts phenoxyethanol, benzyl alcohol, and organic acids. Where applied. Creams, serums, toners, micellar waters at 0.5-1.5%. Often paired with phenoxyethanol and ethylhexylglycerin (Optiphen complex by Schülke). In Spain – background in most mass and pharmacy products (CeraVe, Eucerin, La Roche-Posay). Evidence base. The 2008 CIR review confirmed safety of caprylyl glycol up to 5% in leave-on products. Manufacturer Symrise provides MIC comparisons on 50 strains – the antimicrobial profile is moderately broad. Safety. CIR – safe at use concentrations (up to 5%). Hypoallergenic. Irritation possible above 2% in very sensitive skin – mild stinging. Non-comedogenic, non-photosensitizing. Pregnancy and lactation – safe. Acceptable at any stage. One of the preferred components in phenoxyethanol-free clean-beauty formulas. What to combine with. Universal – compatible with any actives (retinol, AHA/BHA, niacinamide, vitamin C). Standard background component in modern formulas.

Frequently asked questions

Is Caprylyl Glycol safe during pregnancy?

Caprylyl Glycol is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is Caprylyl Glycol for?

Caprylyl Glycol suits: oily, dry, sensitive, combination, normal.

What is Caprylyl Glycol and what does it do in cosmetics?

Multifunctional ingredient that boosts preservatives and works as a mild humectant and conditioner.

What's the INCI name for Caprylyl Glycol?

The INCI name is Caprylyl Glycol.

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