Cysteamine

INCI: Cysteamine Hydrochloride

Antioxidant and melanin degrader, a hydroquinone alternative for stubborn melasma. The main practical downside is a sharp unpleasant odor.

Brightening

Evidence by route

Topical application

Limited evidence. One RCT or several controlled studies with limitations.

Double-blind RCTs show comparable efficacy to hydroquinone 4% in melasma. Slight stinging on skin but without ochronosis risk.

Irritation potential

Medium

Allergen risk

Low

Pregnancy

Caution

Suitable for

NormalOilyCombination

Use with caution

Sensitive

Is Cysteamine safe during pregnancy?

Cysteamine should be used with caution during pregnancy. Consulting a dermatologist or OB-GYN is advisable.

What skin types is Cysteamine for?

Cysteamine suits: normal, oily, combination. Use with caution in: sensitive.

Can Cysteamine irritate the skin?

Cysteamine has moderate irritation potential. Sensitive skin may show a transient reaction that usually settles with adaptation.