N-Acetyl Glucosamine
INCI: Acetyl Glucosamine
Amino sugar, a precursor of hyaluronic acid. Inhibits tyrosinase, so it lightens post-acne marks and melasma, especially when paired with niacinamide. Also supports skin HA synthesis.
Evidence by route
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
Double-blind RCTs with 2% NAG plus 4% niacinamide reduce visible hyperpigmentation significantly better than placebo over 8–10 weeks. Well tolerated, unlike hydroquinone.
- Bissett DL et al. J Cosmet Dermatol. 2007;6(1):20-26.
- Kimball AB et al. Br J Dermatol. 2010;162(2):435-441.
Tolerability and safety
Irritation potential
LowAllergen risk
LowPregnancy
SafeSkin types
Suitable for
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Frequently asked questions
Is N-Acetyl Glucosamine safe during pregnancy?
N-Acetyl Glucosamine is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is N-Acetyl Glucosamine for?
N-Acetyl Glucosamine suits: normal, dry, oily, combination, sensitive.
What is N-Acetyl Glucosamine and what does it do in cosmetics?
Amino sugar, a precursor of hyaluronic acid.
What's the INCI name for N-Acetyl Glucosamine?
The INCI name is Acetyl Glucosamine. It may also appear as: N-Acetyl Glucosamine, NAG, GlcNAc.