Dextran
Polysaccharide forming a thin moisture-retaining film. Common thickener and carrier in serums.
Evidence by route
Topical application
Inert formulation ingredient. Safe, no standalone activity.
How to read tiers A–F
- CWeak evidence. In vitro data, open-label studies, or expert consensus
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
About this ingredient
Dextran is a natural polysaccharide of α-1,6-linked glucose molecules. Produced by Leuconostoc mesenteroides bacteria via sucrose fermentation. Known in medicine as a plasma substitute (Reopolyglucin), in cosmetics – a functional ingredient. Mechanism. On skin it forms a thin hydrophilic film, retains water in the stratum corneum, works as a mild humectant. Molecular weight 5-2000 kDa depending on source – affects texture and sensory feel. In formulas it works as a thickener, active carrier, and emulsion stabilizer. Where applied. Serums, moisturizers, masks, 'gel essence' products. Common in K-beauty lines (Cosrx, Beauty of Joseon) and in 'hyaluronic acid alternative' marketing formulas. In Spain – niche Korean brands, Sesderma products. Evidence base. Humectant properties confirmed in standard TEWL tests. No standalone meaningful skin activity – a functional ingredient with pleasant sensory qualities. Dextran sulfate (a separate derivative) is studied for vascular skin components, but it's a different molecule. Safety. CIR confirmed dextran safety in cosmetic use. Hypoallergenic, non-comedogenic. In patients with a history of severe systemic dextran allergy (anaphylaxis to infusion solutions) sensitization on topical application is theoretically possible – extremely rare in practice. Pregnancy and lactation – safe at cosmetic concentrations. Best suited to: any skin type as one humectant in a multi-component formula.
Frequently asked questions
Is Dextran safe during pregnancy?
Dextran is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What is Dextran and what does it do in cosmetics?
Polysaccharide forming a thin moisture-retaining film.
What's the INCI name for Dextran?
The INCI name is Dextran.
See Dextran in a product composition right on the store page
The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
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