Evigrade

Diglycerin

Humectant, lighter-feeling glycerin analogue. Functional formulation ingredient with no standalone activity on the skin.

Evidence by route

C

Topical application

Inert formulation ingredient. Safe, no standalone activity.

How to read tiers A–F
  • CWeak evidence. In vitro data, open-label studies, or expert consensus

Tolerability and safety

Irritation potential
Low
Allergen risk
Low
Pregnancy
Safe

About this ingredient

Diglycerin is a glycerin dimer, a humectant with a lighter sensory profile than mono-glycerin. Produced from glycerin by catalytic dehydration. Mechanism. Humectant – draws moisture from air and deeper skin layers into the stratum corneum. Higher molecular weight than glycerin, so it feels less sticky and lighter in formulas. Effective at 2-10% – close to glycerin standards. Where applied. Serums, creams, masks, especially in Asian manufacturers' formulas with a 'light moisturizing texture' marketing angle and in oily-skin products. In Spain – niche K-beauty lines, some Sesderma and Cantabria Labs formulas. Evidence base. A functional humectant. Skin moisturization effect confirmed in standard TEWL tests. Effect strength comparable to glycerin; the advantage is in sensory feel, not efficacy. Safety. CIR confirmed diglycerin safe in cosmetic use. Hypoallergenic, non-comedogenic, non-irritating. Systemic absorption through intact skin is low. Pregnancy and lactation – safe. No restrictions. Best suited to: any skin type, especially oily and combination – thanks to the light texture. A solid glycerin alternative for patients who complain about stickiness.

Frequently asked questions

Is Diglycerin safe during pregnancy?

Diglycerin is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What is Diglycerin and what does it do in cosmetics?

Humectant, lighter-feeling glycerin analogue.

What's the INCI name for Diglycerin?

The INCI name is Diglycerin.

See Diglycerin in a product composition right on the store page

The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.

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