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Homosalate

Chemical UVB filter. Often combined with avobenzone to broaden protection. Limited to 10% in the EU due to potential endocrine activity.

Protection

Evidence by route

Topical application

B

Limited evidence. One RCT or several controlled studies with limitations.

FDA approved as a UV filter. SCCS lowered maximum concentration to 7.34% (2021) due to in vitro endocrine activity data. Systemic absorption confirmed in FDA studies – plasma concentrations exceed the threshold requiring additional toxicological data.

  • Matta MK et al. JAMA. 2019;321(21):2082-2091.
  • SCCS Opinion SCCS/1622/20.

Tolerability and safety

Irritation potential

Low

Allergen risk

Low

Pregnancy

Caution

Skin types

Suitable for

NormalCombinationOily

Use with caution

Sensitive

Frequently asked questions

Is Homosalate safe during pregnancy?

Homosalate should be used with caution during pregnancy. Consulting a dermatologist or OB-GYN is advisable.

What skin types is Homosalate for?

Homosalate suits: normal, combination, oily. Use with caution in: sensitive.