EEvigrade
RU

Ascorbyl Tetraisopalmitate

Oil-soluble vitamin C derivative. More stable than L-ascorbic acid with better penetration through the lipid barrier. Converts to ascorbic acid inside the skin.

BrighteningAnti-agingProtection

Evidence by route

Topical application

C

Weak evidence. In vitro data, open-label studies, or expert consensus.

Small clinical studies show brightening and antioxidant effects. Lipophilicity ensures good penetration, but conversion rate to the active form is lower than L-ascorbic acid. No large comparative RCTs.

  • Ochiai Y et al. Skin Pharmacol Physiol. 2006;19(2):89-94.

Tolerability and safety

Irritation potential

Low

Allergen risk

Low

Pregnancy

Safe

Skin types

Suitable for

SensitiveDryNormalCombination

Frequently asked questions

Is Ascorbyl Tetraisopalmitate safe during pregnancy?

Ascorbyl Tetraisopalmitate is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is Ascorbyl Tetraisopalmitate for?

Ascorbyl Tetraisopalmitate suits: sensitive, dry, normal, combination.