Retinaldehyde
INCI: Retinal
Intermediate vitamin A form between retinol and retinoic acid. More potent than retinol but gentler than tretinoin.
Evidence by route
Topical application
AProven efficacy. Two or more independent RCTs with instrumental endpoints.
Studies show comparable activity to retinol with a better tolerability profile. One head-to-head trial demonstrated superiority over retinol in conversion rate and clinical efficacy.
- Creidi P et al. Dermatology. 1998;197(4):363-368.
Working concentrations
0.05–0.1%
Tolerability and safety
Irritation potential
MediumAllergen risk
LowPregnancy
AvoidSkin types
Suitable for
Use with caution
Frequently asked questions
Is Retinaldehyde safe during pregnancy?
Retinaldehyde is not recommended during pregnancy. Consider an alternative from the same category.
What skin types is Retinaldehyde for?
Retinaldehyde suits: normal, combination, oily. Use with caution in: sensitive, dry.
Can Retinaldehyde irritate the skin?
Retinaldehyde has moderate irritation potential. Sensitive skin may show a transient reaction that usually settles with adaptation.