Evigrade

Nicotiana Benthamiana sh-TGF-Beta2

A recombinant growth factor (transforming growth factor beta2) grown in Nicotiana benthamiana tobacco. The maker links it to skin renewal and firmness; independent data are limited. Well tolerated.

Evidence by route

B

Topical application

A biotech growth factor. The maker links it to skin firmness; independent data limited.

  • CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
  • BLimited evidence. One RCT or several controlled studies with limitations

Tolerability and safety

Irritation potential
Low
Allergen risk
Low
Pregnancy
Safe
Suitable for
Normal, Dry, Combination, Oily, Sensitive

About this ingredient

Nicotiana Benthamiana sh-TGF-Beta2 is a recombinant growth factor (transforming growth factor beta2) produced in the tobacco plant Nicotiana benthamiana. In cosmetics it is positioned within anti-aging care, linked to renewal and firmness. Honesty about the evidence matters here. The manufacturer ties this molecule to skin improvement, but independent data are scarce, and the role of growth factors applied to the skin is still debated. It is worth treating as a supporting component of unconfirmed efficacy, not a central active. For topical use it has no systemic relevance, so it can be used during pregnancy and breastfeeding. Tolerance is good, with low irritation and allergy potential, suitable for sensitive skin.

Frequently asked questions

Is Nicotiana Benthamiana sh-TGF-Beta2 safe during pregnancy?

Nicotiana Benthamiana sh-TGF-Beta2 is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is Nicotiana Benthamiana sh-TGF-Beta2 for?

Nicotiana Benthamiana sh-TGF-Beta2 suits: normal, dry, combination, oily, sensitive.

What is Nicotiana Benthamiana sh-TGF-Beta2 and what does it do in cosmetics?

A recombinant growth factor (transforming growth factor beta2) grown in Nicotiana benthamiana tobacco.

What's the INCI name for Nicotiana Benthamiana sh-TGF-Beta2?

The INCI name is Nicotiana Benthamiana sh-TGF-Beta2. It may also appear as: sh-TGF-Beta2.

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