A recombinant growth factor (transforming growth factor beta2) grown in Nicotiana benthamiana tobacco. The maker links it to skin renewal and firmness; independent data are limited. Well tolerated.
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
A biotech growth factor. The maker links it to skin firmness; independent data limited.
Nicotiana Benthamiana sh-TGF-Beta2 is a recombinant growth factor (transforming growth factor beta2) produced in the tobacco plant Nicotiana benthamiana. In cosmetics it is positioned within anti-aging care, linked to renewal and firmness. Honesty about the evidence matters here. The manufacturer ties this molecule to skin improvement, but independent data are scarce, and the role of growth factors applied to the skin is still debated. It is worth treating as a supporting component of unconfirmed efficacy, not a central active. For topical use it has no systemic relevance, so it can be used during pregnancy and breastfeeding. Tolerance is good, with low irritation and allergy potential, suitable for sensitive skin.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Nicotiana Benthamiana sh-TGF-Beta2 is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Nicotiana Benthamiana sh-TGF-Beta2 suits: normal, dry, combination, oily, sensitive.
A recombinant growth factor (transforming growth factor beta2) grown in Nicotiana benthamiana tobacco.
The INCI name is Nicotiana Benthamiana sh-TGF-Beta2. It may also appear as: sh-ТФР-бета2, sh-TGF-Beta2.
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