A recombinant peptide grown in Nicotiana benthamiana tobacco. The maker links it to skin renewal and firmness; independent data are limited. Well tolerated.
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
A biotech peptide. The maker links it to skin firmness; independent data limited.
sh-Polypeptide-9 (INCI Nicotiana Benthamiana sh-Polypeptide-9) is a recombinant peptide grown in the tobacco plant Nicotiana benthamiana through biotechnology. In anti-aging cosmetics it is positioned as a plant-derived growth factor aimed at skin firmness and renewal. Here it is worth being honest about efficacy. The maker links the peptide to renewal and firmness, but independent data is scarce: most studies come from the side that sells it. Count on it as a promising support component, not as an active with proven efficacy. Applied topically it is not systemically relevant, so it can be used during pregnancy and breastfeeding without issue. Tolerability is good. Irritation and allergy potential are both low, which makes it suitable for sensitive skin. There is no data pointing to comedogenicity.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Nicotiana Benthamiana sh-Polypeptide-9 is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Nicotiana Benthamiana sh-Polypeptide-9 suits: normal, dry, combination, oily, sensitive.
A recombinant peptide grown in Nicotiana benthamiana tobacco.
The INCI name is Nicotiana Benthamiana sh-Polypeptide-9. It may also appear as: sh-полипептид-9, sh-Polypeptide-9, Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-9.
Published: · updated: