Evigrade

Nicotiana Benthamiana sh-Polypeptide-9

A recombinant peptide grown in Nicotiana benthamiana tobacco. The maker links it to skin renewal and firmness; independent data are limited. Well tolerated.

Evidence by route

B

Topical application

A biotech peptide. The maker links it to skin firmness; independent data limited.

  • CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
  • BLimited evidence. One RCT or several controlled studies with limitations

Tolerability and safety

Irritation potential
Low
Allergen risk
Low
Pregnancy
Safe
Suitable for
Normal, Dry, Combination, Oily, Sensitive

About this ingredient

sh-Polypeptide-9 (INCI Nicotiana Benthamiana sh-Polypeptide-9) is a recombinant peptide grown in the tobacco plant Nicotiana benthamiana through biotechnology. In anti-aging cosmetics it is positioned as a plant-derived growth factor aimed at skin firmness and renewal. Here it is worth being honest about efficacy. The maker links the peptide to renewal and firmness, but independent data is scarce: most studies come from the side that sells it. Count on it as a promising support component, not as an active with proven efficacy. Applied topically it is not systemically relevant, so it can be used during pregnancy and breastfeeding without issue. Tolerability is good. Irritation and allergy potential are both low, which makes it suitable for sensitive skin. There is no data pointing to comedogenicity.

Frequently asked questions

Is Nicotiana Benthamiana sh-Polypeptide-9 safe during pregnancy?

Nicotiana Benthamiana sh-Polypeptide-9 is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is Nicotiana Benthamiana sh-Polypeptide-9 for?

Nicotiana Benthamiana sh-Polypeptide-9 suits: normal, dry, combination, oily, sensitive.

What is Nicotiana Benthamiana sh-Polypeptide-9 and what does it do in cosmetics?

A recombinant peptide grown in Nicotiana benthamiana tobacco.

What's the INCI name for Nicotiana Benthamiana sh-Polypeptide-9?

The INCI name is Nicotiana Benthamiana sh-Polypeptide-9. It may also appear as: sh-Polypeptide-9, Nicotiana Benthamiana Hexapeptide-40 sh-Polypeptide-9.

See Nicotiana Benthamiana sh-Polypeptide-9 in a product composition right on the store page

The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.

Install the extension for free

Similar role in the formula

Explore by category

Anti-aging

Published: · updated: