Oleoyl Dipeptide-15
A synthetic peptide. Makers link it to support for skin comfort and firmness; independent evidence is still limited. Well tolerated.
Evidence by route
Topical application
A peptide active. Well tolerated; independent data limited.
- CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
- BLimited evidence. One RCT or several controlled studies with limitations
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Normal, Dry, Combination, Oily, Sensitive
About this ingredient
Oleoyl Dipeptide-15 is a synthetic peptide linked to an oleic acid chain, which improves its affinity with the oil phase of a formula. Manufacturers tie it to skin comfort and elasticity, within the logic of skincare peptides. On efficacy it is fair to be honest: independent evidence is still thin. What exists comes mostly from the supplier rather than from broad outside studies. It is a reasonable support ingredient, not an active with the firm backing of retinoids or vitamin C. Useful as an add-on, without expecting a visible change on its own. Applied topically there is no meaningful systemic absorption, so it can be used during pregnancy and breastfeeding. Tolerance is good: low irritation and allergy potential, suitable for sensitive skin. Peptides of this type rarely cause a reaction and fit well into fuller routines.
Frequently asked questions
Is Oleoyl Dipeptide-15 safe during pregnancy?
Oleoyl Dipeptide-15 is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Oleoyl Dipeptide-15 for?
Oleoyl Dipeptide-15 suits: normal, dry, combination, oily, sensitive.
What is Oleoyl Dipeptide-15 and what does it do in cosmetics?
A synthetic peptide.
What's the INCI name for Oleoyl Dipeptide-15?
The INCI name is Oleoyl Dipeptide-15.
See Oleoyl Dipeptide-15 in a product composition right on the store page
The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
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Ingredients in the same category
Oleoyl Tetrapeptide-31, Oligopeptide-2, Oligopeptide-4, Oryza Sativa Bran Extract, Retinol, Vaccinium Angustifolium (Blueberry) Fruit Extract, Carnosine, Hesperidin Methyl Chalcone
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