Oleoyl Tetrapeptide-31
A synthetic peptide. Makers link it to support for skin renewal; independent evidence is still limited. Well tolerated.
Evidence by route
Topical application
A peptide active. Well tolerated; independent data limited.
- CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
- BLimited evidence. One RCT or several controlled studies with limitations
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Normal, Dry, Combination, Oily, Sensitive
About this ingredient
Oleoyl Tetrapeptide-31 is a synthetic peptide bound to an oleic acid chain, which gives it affinity with the oil phase. Manufacturers link it to support for skin renewal, within the family of cosmetic peptides. On efficacy, the fair point is that independent evidence is still thin. The data comes mostly from the supplier rather than broad outside studies. It works as a support ingredient, not as an active with firm backing like a retinoid. It makes sense as an add-on within a routine, without expecting a result from it alone. Applied topically there is no meaningful systemic absorption, so it can be used during pregnancy and breastfeeding. Tolerance is good: low irritation and allergy potential, suitable for sensitive skin. Peptides of this class rarely cause a reaction and combine well with other common ingredients.
Frequently asked questions
Is Oleoyl Tetrapeptide-31 safe during pregnancy?
Oleoyl Tetrapeptide-31 is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Oleoyl Tetrapeptide-31 for?
Oleoyl Tetrapeptide-31 suits: normal, dry, combination, oily, sensitive.
What is Oleoyl Tetrapeptide-31 and what does it do in cosmetics?
A synthetic peptide.
What's the INCI name for Oleoyl Tetrapeptide-31?
The INCI name is Oleoyl Tetrapeptide-31.
See Oleoyl Tetrapeptide-31 in a product composition right on the store page
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Oligopeptide-2, Oligopeptide-4, Oryza Sativa Bran Extract, Oxidized Glutathione, Retinyl Acetate, Vaccinium Macrocarpon Fruit Extract, Centella Asiatica Oil, Hexapeptide-10
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