A peptide active. The maker links it to firmness and skin renewal; independent data are limited. Well tolerated.
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
A peptide active. Well tolerated; independent data limited.
Acetyl tetrapeptide-11 (INCI: Acetyl Tetrapeptide-11) is a synthetic signaling peptide used in anti-aging cosmetics. The supplier links it to improved firmness and skin renewal, in theory by stimulating cell-adhesion proteins. Honesty is in order here: much of the data come from the supplier, and independent evidence is thin. It is a supporting active with a subtle effect within an anti-aging routine, not an ingredient that will change the skin on its own. Compared with retinoids or vitamin C, its evidence base is smaller. Topically it is not systemically relevant, so it can be used during pregnancy and breastfeeding without concern. Tolerance is high, with low irritation and allergy potential, suitable for sensitive skin.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Acetyl Tetrapeptide-11 is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Acetyl Tetrapeptide-11 suits: normal, dry, combination, oily, sensitive.
A peptide active.
The INCI name is Acetyl Tetrapeptide-11. It may also appear as: Ацетил тетрапептид-11.
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