Acetyl Tetrapeptide-3
A synthetic peptide. The maker links it to skin density and firmness; independent data are limited. Well tolerated.
Evidence by route
Topical application
A peptide active. The maker links it to skin firmness; independent data limited.
- CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
- BLimited evidence. One RCT or several controlled studies with limitations
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Normal, Dry, Combination, Oily, Sensitive
About this ingredient
Acetyl Tetrapeptide-3 is a short-chain synthetic peptide, acetylated for better stability. In serums and creams it appears in formulas aimed at skin density and firmness, and also in products meant to strengthen hair. On efficacy, expectations should be kept in check. The manufacturer links it to an effect on the skin's support matrix, but independent data are scarce. It is reasonable to see it as a supporting component within an anti-aging formula rather than its mainstay. For topical use it has no systemic relevance, so it can be used during pregnancy and breastfeeding. Tolerance is good, with low irritation and allergy potential, which makes it suitable for sensitive skin.
Frequently asked questions
Is Acetyl Tetrapeptide-3 safe during pregnancy?
Acetyl Tetrapeptide-3 is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Acetyl Tetrapeptide-3 for?
Acetyl Tetrapeptide-3 suits: normal, dry, combination, oily, sensitive.
What is Acetyl Tetrapeptide-3 and what does it do in cosmetics?
A synthetic peptide.
What's the INCI name for Acetyl Tetrapeptide-3?
The INCI name is Acetyl Tetrapeptide-3.
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