A synthetic peptide. The maker links it to skin density and firmness; independent data are limited. Well tolerated.
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
A peptide active. The maker links it to skin firmness; independent data limited.
Acetyl Tetrapeptide-3 is a short-chain synthetic peptide, acetylated for better stability. In serums and creams it appears in formulas aimed at skin density and firmness, and also in products meant to strengthen hair. On efficacy, expectations should be kept in check. The manufacturer links it to an effect on the skin's support matrix, but independent data are scarce. It is reasonable to see it as a supporting component within an anti-aging formula rather than its mainstay. For topical use it has no systemic relevance, so it can be used during pregnancy and breastfeeding. Tolerance is good, with low irritation and allergy potential, which makes it suitable for sensitive skin.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Acetyl Tetrapeptide-3 is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Acetyl Tetrapeptide-3 suits: normal, dry, combination, oily, sensitive.
A synthetic peptide.
The INCI name is Acetyl Tetrapeptide-3. It may also appear as: Ацетил тетрапептид-3.
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